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Hypoxemia clinical trials

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NCT ID: NCT04410757 Completed - Hypotension Clinical Trials

Point of Care Ultrasound Evaluation in the Post-Anesthesia Unit

Start date: August 1, 2018
Phase:
Study type: Observational

The purpose of this observational research study is to examine how point-of care ultrasound affects the workup and management of perioperative complications for specific clinical scenarios of low blood pressure (hypotension), low blood oxygen (hypoxemia), in the post- anesthesia care unit (PACU).

NCT ID: NCT04383821 Completed - Hypoxemia Clinical Trials

Comparison of the Non-rebreather Mask With the Double-trunk Mask

Start date: May 15, 2020
Phase: N/A
Study type: Interventional

This study will compare the impact of the Double-Trunk Mask (DTM) with the Non-Rebreather Mask (NRM) on the blood gases of patients with severe hypoxemia.

NCT ID: NCT04346693 Completed - Pneumonia Clinical Trials

An Open Randomized Study of Dalargin Efectiveness in Combination With Leitragin Drug in Patients With Severe and Critical Manifestations of SARS-COVID-19

Start date: April 8, 2020
Phase: Phase 3
Study type: Interventional

The purpose of the study is to evaluate an effectiveness of the drug Dalargin in combination with Leitragin for the prevention and treatment of severe pulmonary complications symptoms associated with severe and critical coronavirus infection cases (SARS COVID19, expanded as Severe acute respiratory syndrome Cоrona Virus Disease 2019 ). Test drugs that will be administered to patients are: - Leitragin, solution for inhalation administration, - Dalargin, solution for intravenous and intramuscular administration.

NCT ID: NCT04346420 Completed - COVID Clinical Trials

Impact of the Double-Trunk Mask on Oxygenation Titration in COVID-19

Start date: April 9, 2020
Phase: N/A
Study type: Interventional

This study will investigate the impact of the Double-Trunk Mask (DTM) on the reduction of oxygen titration in patients with severe hypoxemia.

NCT ID: NCT04241861 Completed - Respiratory Failure Clinical Trials

High-flow Nasal Cannula vs. Helmet PSV vs. Helmet CPAP During Respiratory Failure

HIGHFLOWHELMET
Start date: January 22, 2020
Phase: N/A
Study type: Interventional

The investigators designed a cross-over, randomized trial to assess the physiological effects of helmet pressure support ventilation (PSV) and continuous positive airway pressure (CPAP) as compared to high-flow nasal cannula during the early phase of acute hypoxemic respiratory failure

NCT ID: NCT04159116 Completed - Hypoxemia Clinical Trials

Prevention and Treatment of Laryngospasm and Hypoxemia Based on Risk Factors in Adult Outpatients Undergoing EGD

Start date: November 4, 2019
Phase: N/A
Study type: Interventional

The purpose of this study is to identify patient and provider-chosen factors that put patients at risk for the development of hypoxemia (oxygen saturation < 90% for 5 seconds) during endoscopy and to use this knowledge to develop a treatment protocol for specific causes of hypoxemia in adult esophagogastroduodenoscopy outpatients.

NCT ID: NCT04081142 Completed - Respiratory Failure Clinical Trials

Application of Indicator Based-electrical Impedance Tomography Method Assess Lung Regional Perfusion in ICU Patients

Start date: May 1, 2018
Phase:
Study type: Observational

This study is an observational study. Investigate the relationship of oxgenation and lung regional ventilation and perfusion assessed by the indicator based-EIT method in the critically ill patients in ICU

NCT ID: NCT03968120 Completed - Pneumonia Clinical Trials

Effect of Lung Protective One-lung Ventilation With Fix and Variable PEEP on Oxygenation and Outcome

Start date: February 1, 2018
Phase: N/A
Study type: Interventional

During One-lung ventilation, the use of lower tidal volumes (VT) is helpful to avoid over-distension, provide sufficient oxygenation, but can result in increased atelectasis. Nevertheless, it is not known if, during one-lung ventilation with constant low VT, moderate levels of PEEP combined with lung recruitment maneuvers are superior to variable PEEP for intraoperative oxygenation and protection against PPCs. Aim of the study is to compare a strategy using constant tidal volume with recruitment maneuvers versus variable PEEP with recruitment maneuvers during thoracic surgery in adults. The investigators hypothesize that in adult, non-obese patients undergoing thoracic surgery under standardized OLV with variable PEEP and recruitment maneuvers as compared to constant PEEP without recruitment maneuvers prevent PPCs. Patients will be randomly assigned to one of two groups: FIX PEEP VOLUME GROUP (Groupfix): mechanical ventilation with constant (6 ml/kgIBW) tidal volume and PEEP of 5 cmH2O with recruitment maneuvers VARIABLE PEEP GROUP (Groupvar): mechanical ventilation with constant (6 ml/kgIBW) tidal volume with variable PEEP with recruitment maneuvers.

NCT ID: NCT03944967 Completed - Respiratory Failure Clinical Trials

Postoperative Remote Monitoring of Vital Signs in Older Cardiac Surgery Patients

AGEAWARE
Start date: March 5, 2020
Phase:
Study type: Observational

A significant number of elderly patients experience a complication after cardiac surgery. This study aims to determine if postoperative remote monitoring of vital signs can be used to identify medicatie risk factors for vital sign deterioration in older cardiac surgery patients. - Single center pilot study. - 100 older patients undergoing cardiac surgery. - Continuous remote monitoring of vital signs after ICU discharge - Main study endpoint is vital sign deterioration.

NCT ID: NCT03851783 Completed - Pneumonia Clinical Trials

Solar Oxygen Study

SOS
Start date: July 1, 2019
Phase: N/A
Study type: Interventional

Globally, approximately 7.7 million children per year die before the age of 5 years. Infectious diseases account for a large proportion of these deaths, with pneumonia being the leading cause of mortality (2.1 million deaths/year). Most deaths occur in resource-poor settings in Asia and Africa. Oxygen (O2) therapy is essential to support life in these patients. Large gaps remain in the case management of children presenting to African hospitals with respiratory distress, including essential supportive therapies such as supplemental oxygen. In resource-constrained settings, oxygen delivery systems can lead to measurable improvements in survival from childhood pneumonia. A multihospital effectiveness study in Papua New Guinea demonstrated a reduction in mortality from childhood pneumonia from 5.0% to 3.2% (35% reduction in mortality) after implementation of enhanced oxygen delivery system. The investigators propose to investigate a novel strategy for oxygen delivery that could be implemented in remote locations with minimal access to an electrical power supply: solar-powered oxygen (SPO2).