Inferior Vena Cava Assessment in Term Pregnancy Using Ultrasound: a

Status Completed

Clinical Trial Summary

This study is to assess the feasibility of 2 different ultrasound views of the inferior vena cava (IVC), a large vein that returns blood to the heart. Ultrasound is safe in pregnancy and, is regularly used to evaluate the fetus. It is hoped that imaging of the IVC will then allow us to determine the fluid status of the parturient which could be helpful in treating hemodynamic instability. This study will not involve any change in management of the participating patients.

Clinical Trial Description

Anesthesiology consultants and trainees with US experience will first perform scans from the RUQ view starting on the mid-axillary line at the T4 intercostal space, looking to obtain a view of the IVC as it enters the right atrium (RA). Following successful acquisition, the examiner will perform scan from the subxiphoid position, looking to obtain the same view of the IVC transitioning into the RA. Primary endpoint will be time to obtaining quality of images. The investigator will use a stopwatch to time acquisition of images. If the duration of scanning exceeds ten minutes, the scan will be discontinued and labeled as failed. Each image will be separately reviewed by 2 different US specialists with extensive US experience. Images will be assessed according to a Likert scale from 1 to 5. (Very poor (1), poor (2), acceptable (3), good (4), very good (5)) Secondary endpoints will be assessed as follows: 1. Acceptability: all patients participating in the study will complete a questionnaire to assess acceptability. 2. Comfort: During the exam the patient will have the option to suspend the scan by stating they are uncomfortable and wish to stop. Each request will be noted and taken into the account at data analysis. Furthermore, patients will be given a questionnaire at the end of the scan and asked to rate their comfort level during procedure according to Likert scale. (Very comfortable (5), comfortable (4), equivocal (3), uncomfortable (2), very uncomfortable (1)) 3. Ease of exam: Examiner will rate the ease of image acquirement according to Likert scale. (impossible (1), difficult (2), equivocal (3), easy (4), very easy (5)) ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02584803
Study type	Observational
Source	Lawson Health Research Institute
Contact
Status	Completed
Phase
Start date	May 2016
Completion date	September 2017

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04062994` - A Clinical Decision Support Trial to Reduce Intraoperative Hypotension
Active, not recruiting	`NCT02016599` - Effects of Transitional Circulation in ELBW Infants
Recruiting	`NCT05836610` - Hydrocortisone Therapy Optimization During Hypothermia Treatment in Asphyxiated Neonates	Phase 4
Suspended	`NCT02315937` - Hemodynamic Assessment During Spinal Anesthesia Using Transthoracic Echocardiography'	N/A
Completed	`NCT02907931` - Carotid Doppler Ultrasound for the Measurement of Intravascular Volume Status	N/A
Completed	`NCT03215797` - Phenylephrine or Norepinephrine for a Better Hemodynamic Stability	Phase 3
Recruiting	`NCT02532270` - Detecting Hypotension By Continuous Non-invasive Arterial Pressure Monitoring	N/A
Completed	`NCT02437799` - Dicrotic Notch and Hypotension at Caesarean Under Spinal Anaesthesia	N/A
Completed	`NCT02802683` - Hemodynamic Impact of Hyperbaric Versus Isobaric for Spinal Anesthesia During Cesarean Delivery	Phase 4
Completed	`NCT02146898` - The Severity Of Hypotension Comparing Three Positions During Spinal Anesthesia For Cesarean Delivery	N/A
Completed	`NCT01930227` - Transcutaneous Electrical Acupoint Stimulation(TEAS) for Hypotension After Spinal Anesthesia in Parturients	N/A
Not yet recruiting	`NCT01941472` - Transcutaneous pO2, Transcutaneous pCO2 and Central Venous pO2 Variations to Predict Fluid Responsiveness	N/A
Recruiting	`NCT01434251` - Treatment of Hypotension of Prematurity (TOHOP)	N/A
Completed	`NCT01592669` - Passive Leg Raising Attenuates and Delays Tourniquet Deflation-induced Hypotension and Tachycardia	N/A
Withdrawn	`NCT01183741` - Accuracy of Non-Invasive Blood Pressure Measurement in Adults	Phase 3
Completed	`NCT00991627` - Different Approaches to Maternal Hypotension During Cesarean Section	Phase 4
Withdrawn	`NCT00750516` - Lactic Acid Levels In Hypotensive Patients Without(Standard) and With Tourniquet
Completed	`NCT00115726` - Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure	Phase 4
Recruiting	`NCT05513066` - Management Arterial Hypotension During Planned Caesarean Section, Intravenous Ephedrine/Phenylephrine Mixture Versus Intravenous Baby Noradrenaline
Completed	`NCT04089644` - Manual vs Closed-loop Control of Mean Arterial Pressure	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Inferior Vena Cava Assessment in Term Pregnancy Using Ultrasound: a Feasibility Study of Subxiphoid and RUQ Views

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms