Hypovolemic Shock Clinical Trial
— HMDIHOfficial title:
Comparison of CVP Values , ΔPP and Echocardiographic at Different Angles Headwaters Before and After Volume Challenge
The purpose of this study is to determine whether hemodynamic measures vary in angles bedside before and after volume challenge.
Status | Recruiting |
Enrollment | 30 |
Est. completion date | May 2014 |
Est. primary completion date | September 2013 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 60 Years |
Eligibility |
Inclusion Criteria: - Being in circulatory shock and have at least one of the following criteria to identify loss of tissue perfusion: systolic blood pressure <90 mmHg or need for vasoactive drugs, urine output below 0.5 ml / kg / h. - Being under sedation, assessed by the scale of Richmond agitation and sedation (RASS) -5, mechanically ventilated in volume control mode with tidal volume between 8 to 12 ml/kg, PEEP to 8 cm H2O. - Tue signing the informed consent by legal guardian. Exclusion Criteria: - Presence cardiac arrhythmias. - Presence of abdominal or thoracic trauma. - Contraindication for passive elevation of the members. - Hypoxia significant PaO2/FiO2 < or equal 100. |
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Diagnostic
Country | Name | City | State |
---|---|---|---|
Brazil | Intensive Care Unit, Clinical Hospital, Federal University of Uberlandia | Uberlandia | Minas Gerais |
Lead Sponsor | Collaborator |
---|---|
Federal University of Uberlandia |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Different Backrest position's effect on CVP, CO and ?PP measures | Data collection was performed at admission or within 10 days of hospitalization between September 2013 and February 2014. | Yes |
Status | Clinical Trial | Phase | |
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