Clinical Trials Logo
  1. Home
  2. Hypothermia
  3. NCT01213628

Local CO2 Increases Core and Wound Temperature

Hypothermia Clinical Trial

Official title:
Intraoperative Local Insufflation of Humidified Warmed CO2 Increases Core and Open Wound Temperatures? - A Randomized Clinical Trial

Clinical Trial Summary

Eighty adult patients undergoing open colon surgery will be randomized to either:standard warming measures or to additional insufflation of humidified carbon dioxide in the open wound cavity during major abdominal surgery.

PRIMARY AIM is to test if core and local temperature can be increased.

Clinical Trial Description

Eighty adult patients undergoing open colon surgery will be randomized to either:

standard warming measures including heating sheets, warming of fluids, and insulation of limbs and head, or to additional insufflation of humidified carbon dioxide (approx. 30ºC, approx. 80-100% relative humidity) via a simple humidifier (sterile warmed water) connected to a gas diffuser (Cardia Innovation AB) that is able to create a local atmosphere of 100% carbon dioxide (humidified ) in the open wound cavity.

PRIMARY AIM The primary aim of this study is to evaluate if humidified carbon dioxide insufflated into an open surgical wound can be used to warm the core, open wound cavity, and the wound edges during major abdominal surgery.

SECONDARY AIMS Secondary aims are to evaluate possible differences between the groups regarding complications and clinical differences including histological signs. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01213628
Study type Interventional
Source Karolinska University Hospital
Contact
Status Completed
Phase N/A
Start date March 2007
Completion date May 2008
View Details
See also
  Status Clinical Trial Phase
Completed NCT05669313 - The Effects of Hypothermia and Acidosis on Coagulation During Treatment With Rivaroxaban Measured With ROTEM
Not yet recruiting NCT05306392 - Effects of Induced Moderate Hypothermia on ARDS Patients Under Venovenous ExtraCorporeal Membrane Oxygenation N/A
Completed NCT02685176 - Head and Torso Rewarming Using a Human Model for Severe Hypothermia N/A
Withdrawn NCT02812069 - WarmSmart Warming Protocol N/A
Completed NCT02586974 - Effects of Warmed, Humidified CO2 Insufflation on Body Core Temperature and Cytokine Response N/A
Completed NCT02121574 - Accuracy of Zero-flux and Ingestible Thermometers N/A
Completed NCT02742818 - Forced-air Warming in Endovascular Surgery: Testing Effectiveness of Two Different Blanket Models N/A
Not yet recruiting NCT02211703 - National Epidemiologic Survey on the Incidence of Perioperative Hypothermia N/A
Completed NCT02177903 - Study to Determine the Effects of Pre-warming on OR Patient Temperatures and Surgical Outcomes N/A
Recruiting NCT01866384 - Targeted Temperature Management After Intracerebral Hemorrhage Phase 2
Active, not recruiting NCT01529658 - Renal Hypothermia During Partial Nephrectomy N/A
Completed NCT01722955 - Pre-warmed Intravenous Fluids and Monitored Anesthesia Care N/A
Completed NCT01793337 - Core Body Temperature Measurement During Hot and Cold Environmental Exposure N/A
Completed NCT01559675 - Trial Comparing Low Dose and High Dose Steroids in Patients Undergoing Colorectal Surgery N/A
Terminated NCT01018576 - Delayed Cord Clamping in Premature Infants N/A
Completed NCT00904228 - Plastic Hat Trial to Prevent Hypothermia in Preterm Newborns in the Delivery Room N/A
Terminated NCT00822796 - Thermogard™ Efficacy Trial N/A
Completed NCT00334360 - Dexmed/Buspirone Synergism on Shivering Phase 4
Not yet recruiting NCT06283771 - The Effect of Heated Socks Developed With Wearable Technology on Hypothermia, Thermal Comfort Perception and Shivering N/A
Completed NCT04399902 - Study to Actively Warm Trauma Patients N/A