Hypothermia Clinical Trial
— SjO2Official title:
Cerebral Metabolism During Therapeutic Hypothermia for Cardiac Arrest
Verified date | April 2015 |
Source | Policlinico Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | Italy: Ministry of Health |
Study type | Observational |
The purpose of this study is to understand what happens to cerebral metabolism during therapeutic hypothermia for hypoxic brain injury following cardiac arrest.
Status | Completed |
Enrollment | 15 |
Est. completion date | December 2014 |
Est. primary completion date | December 2014 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 85 Years |
Eligibility |
Inclusion Criteria: - Adult patients in coma after cardiac arrest undergoing therapeutic hypothermia Exclusion Criteria: - Age < 18 - Pregnancy - Traumatic brain injury - Contraindications to cannulation as severe coagulopathy |
Observational Model: Case-Only, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Italy | Intensive Care Unit-Fondazione Ospedale Maggiore Policlinico Mangiagalli Regina Elena | Milan |
Lead Sponsor | Collaborator |
---|---|
Policlinico Hospital |
Italy,
Bernard SA, Gray TW, Buist MD, Jones BM, Silvester W, Gutteridge G, Smith K. Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. N Engl J Med. 2002 Feb 21;346(8):557-63. — View Citation
Macmillan CS, Andrews PJ. Cerebrovenous oxygen saturation monitoring: practical considerations and clinical relevance. Intensive Care Med. 2000 Aug;26(8):1028-36. Review. — View Citation
Nolan JP, Morley PT, Vanden Hoek TL, Hickey RW, Kloeck WG, Billi J, Böttiger BW, Morley PT, Nolan JP, Okada K, Reyes C, Shuster M, Steen PA, Weil MH, Wenzel V, Hickey RW, Carli P, Vanden Hoek TL, Atkins D; International Liaison Committee on Resuscitation. Therapeutic hypothermia after cardiac arrest: an advisory statement by the advanced life support task force of the International Liaison Committee on Resuscitation. Circulation. 2003 Jul 8;108(1):118-21. — View Citation
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