Hypothermia's Effect on Hepatitis B Vaccination

Status Recruiting

Clinical Trial Summary

The purpose of the research is to determine if the Hepatitis B vaccine after birth provides enough protection after cooling for Hypoxic Ischemic Encephalopathy (HIE). To do this, Hepatitis B titers (blood sample) would be taken before, during, and after administering of the Hepatitis B vaccine series to measure efficacy of the vaccine.

Clinical Trial Description

Despite the current research on Hypoxic Ischemic Encephalopathy (HIE), and the known effects of hypothermia on acute immune response, the effect of the hypothermia protocol for HIE on the efficacy of the Hepatitis B vaccine is still unknown. We plan to measure anti-hepatitis B surface antibodies at intervals prior, during, and after the primary Hepatitis B vaccine schedule for individuals with HIE to see if there is any effect on efficacy due to the Hypothermia protocol. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05787899
Study type	Observational
Source	Medical University of South Carolina
Contact	Florian Capobianco, DO
Phone	(843)-792-1414
Email	Capobian@musc.edu
Status	Recruiting
Phase
Start date	May 18, 2023
Completion date	January 1, 2025

View Details

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