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Intra Amniotic Injection of DIGOXIN for Feticide in Second Trimester Termination of Pregnancy

Hypotension Clinical Trial

Official title:
The Safety and Outcome of Intra-amniotic DIGOXIN Injection for Feticide Prior to Second Trimester Abortion

Clinical Trial Summary

In second trimester abortion above 22 weeks the investigators usually inject intra-cardiac Kcl for feticide. Digoxin intra-amniotic injection has been described in the literature in doses of 1-1.5 mg. with a success rate of about 80%, and up to 24 weeks. Our aim in this study is to investigate the safety and success rate of 1.5-2 mg. digoxin, intra-amniotic up to 30 weeks pregnancy .

Clinical Trial Description

- The digoxin will be injected intra-amniotic with U.S guided, trying to avoid any placental passage or intravascular injection /

- Any patient will have prior to the procedure a full examination including E.C.G and cardiac clearance. ;

Study Design

Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01951079
Study type Interventional
Source Meir Medical Center
Contact Zvi Klein, M.D
Phone 972-9-7472544
Email kleinz@clalit.org.il
Status Not yet recruiting
Phase Phase 3
Start date November 2013
Completion date December 2014
View Details
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