Transcutaneous pO2, Transcutaneous pCO2 and Central Venous pO2 Variations to Predict Fluid Responsiveness

Hypotension Clinical Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT01941472
• Other study ID #: MICU2013-1
• Status: Not yet recruiting
• Phase: N/A
• First received: August 31, 2013
• Last updated: September 9, 2013
• Start date: September 2013

Study information

• Verified date: September 2013
• Source: Peking Union Medical College Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: China: Food and Drug Administration
• Study type: Interventional

Clinical Trial Summary

Fluid challenge is often carried out in critical ill patients. Its responsiveness usually requires invasive monitoring. To use non-invasive methods is very tempting. We hypothesize that transcutaneous pO2,transcutaneous pCO2 and Central Venous pO2 variations provide feasible estimation on fluid responsiveness in critical ill patients.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 30
• Est. primary completion date: August 2014
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• 18 years and older ICU patients;

• Hypotension or shock;

• Monitored with PICCO or Swan-Ganz catheter;

• The decision of fluid challenge made by the treating physician;

Exclusion Criteria:

• Evidence of fluid overload;

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Screening

Related Conditions & MeSH terms

• Fluid Challenge
• Fluid Responsiveness
• Hypotension
• Shock

Intervention

Other:
• fluid administration

Locations

Country	Name	City	State
China	MICU of Peking Union Medical College Hospital	Beijing	Beijing
China	MICU of Peking Union Medical College Hospital	Peking	Beijing

Sponsors (1)

Lead Sponsor	Collaborator
Peking Union Medical College Hospital

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Area Under Roc Curve		About one year	No