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Hypotension clinical trials

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NCT ID: NCT00664079 Terminated - Respiratory Failure Clinical Trials

Thyroid Hormones in Critically Ill Children

Thyroid
Start date: October 2005
Phase: N/A
Study type: Observational

Thyroid hormones are substances naturally made by the body and are important to many of your body's basic functions such as breathing and brain function. We are investigating whether or not these hormones are at lower levels in critically ill children which could lead to further health problems. We hope to get a better understanding of hormone levels and their effects on critically ill children to better help other children in the future.

NCT ID: NCT00581477 Terminated - Clinical trials for Orthostatic Hypotension

Treatment of Orthostatic Hypotension

Start date: January 2004
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to try different medications in patients with low blood pressure and other problems with their involuntary (autonomic) nervous system. The pharmacological trials in this study will perhaps lead to more effective treatment. The protocol includes single dose trials, dose-selection trials, 5-day trials and chronic (approximately 2 months) trials, although only dose-selection trials were consistently performed and have results presented.

NCT ID: NCT00576524 Terminated - Clinical trials for End Stage Renal Disease

Application of Impedance Threshold Device Technologies to Treat and Prevent Hypotension During Dialysis

ITD
Start date: September 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the application of the impedance threshold device during hemodialysis in children to optimize fluid removal, reduce the incidence of complications (such as cramps,vomiting and hypotension), and device tolerance.

NCT ID: NCT00330512 Terminated - Clinical trials for Elective Cesarean Section

Maternal Hypotension During Cesarean Section and Short Term Neonatal Outcome.

Start date: May 2006
Phase: Phase 1
Study type: Observational

About 20-25% of deliveries are by cesarean section. Most are elective with use of regional anesthesia (spinal/epidural). Drop of blood pressure after regional anesthesia is common. It have the risk of reduction of blood flow to the placenta and the fetus. No studies had followed the newborns their first days of live,of mothers who developed hypotension in durins CS.

NCT ID: NCT00237783 Terminated - Hypotension Clinical Trials

Safety of Dialysate Sodium Individualization in Hemodialysis Patients With Intradialytic Hypotension

Start date: October 2005
Phase: Phase 1
Study type: Interventional

Low blood pressure (hypotension) during dialysis afflicts approximately 25% of hemodialysis patients. In this pilot study, we will evaluate the safety and effects of individualizing the sodium concentration in the dialysate according to the patient's own plasma sodium levels. We hypothesize that patients will have less thirst and less weight gain during the intervention leading to easier fluid removal and less episodes of hypotension.

NCT ID: NCT00137319 Terminated - Clinical trials for Orthostatic Hypotension

Impedance Threshold Device Tilt Study

Start date: October 2004
Phase: N/A
Study type: Interventional

This study will see if a special piece of equipment can help burn patients who have been in bed for a long time to get out of bed without feeling dizzy or faint.

NCT ID: NCT00046163 Terminated - Clinical trials for Hypotension, Orthostatic

A Phase IV Study in Subjects With Neurogenic Orthostatic Hypotension

Start date: September 5, 2002
Phase: Phase 4
Study type: Interventional

We are seeking male and female patients to voluntarily take part in a clinical research study. Patients must be aged 18 or older and diagnosed with symptomatic orthostatic hypotension (low blood pressure while in the upright position) due to Parkinson's disease, multiple system atrophy, pure autonomic failure or autonomic neuropathies (i.e. neurogenic orthostatic hypotension). Symptoms of low blood pressure include dizziness, lightheadedness, changes in vision and generalized weakness upon standing. The main effect of the drug being studied is to increase blood pressure in the upright position so symptoms will decrease. The purpose of this clinical study is to further assess the clinical effect of high dose midodrine hydrochloride (ProAmatine®), an approved treatment for orthostatic hypotension. During the course of the study, participants will receive either ProAmatine® or a placebo. Assessments will be made using questionnaires that measure symptom and activity levels. Blood pressure in the lying down, sitting and standing positions will be measured. Patients will also complete standing time assessments. They will be asked to remain standing without moving until they feel sufficiently lightheaded, or dizzy, or feel faint so that they would feel more comfortable sitting down.