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Hypotension clinical trials

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NCT ID: NCT04486612 Completed - Clinical trials for Spinal Anesthetics Causing Adverse Effects in Therapeutic Use

Ultrasonographic Measurement of Internal Jugular Vein as a Predictor of Hypotension Following Spinal Anesthesia

IJV
Start date: January 1, 2020
Phase:
Study type: Observational

Hypotension after spinal anesthesia is associated with significant perioperative morbidity and mortality, especially in hypovolemic patients. Ultrasonographic measurement of internal jugular vein (IJV) has been recently shown as effective in predicting the intravascular volume status. The aim was to investigate the reliability of preanesthetic ultrasound measurements of IJV in predicting hypotension after spinal anesthesia.

NCT ID: NCT04463394 Completed - Hypotension Clinical Trials

The Hemodynamic Effects of Vasopressin in Patients With Fontan Physiology

Start date: August 12, 2020
Phase: Early Phase 1
Study type: Interventional

The goal of this study is to evaluate if vasopressin can elevate systemic arterial blood pressures without having a significant effect on pulmonary arterial pressures. Because patients who have undergone Fontan procedures rely on low pressures across the pulmonary vascular bed to maintain cardiac output, vasoactive agents that concomitantly increase systemic and pulmonary pressures may have a deleterious effect in this specific patient population. Hypothesis: In patients with Fontan physiology, vasopressin will increase systemic BP by 20% above baseline, without increasing the transpulmonary gradient.

NCT ID: NCT04433416 Completed - Delirium Clinical Trials

Hypertension and Controlled Hypotension in the Elderly

Start date: June 14, 2020
Phase:
Study type: Observational [Patient Registry]

Comparision of Exposed Factors of Preoperative Hypertension and Intraoperative Controlled Hypotension on Postoperative Delirium in the Elderly under Radical Resection of Head, Neck and Maxillofacial Tumor

NCT ID: NCT04410757 Completed - Hypotension Clinical Trials

Point of Care Ultrasound Evaluation in the Post-Anesthesia Unit

Start date: August 1, 2018
Phase:
Study type: Observational

The purpose of this observational research study is to examine how point-of care ultrasound affects the workup and management of perioperative complications for specific clinical scenarios of low blood pressure (hypotension), low blood oxygen (hypoxemia), in the post- anesthesia care unit (PACU).

NCT ID: NCT04406051 Completed - Hypotension Clinical Trials

Prevention of Maternal Hypotension During Cesarean Section With Norepinephrine Infusion.

annie-manos
Start date: May 26, 2020
Phase: N/A
Study type: Interventional

This will be a randomized study aiming at investigating the combination of a norepinephrine infusion and colloid preloading versus the combination of a norepinephrine infusion and crystalloid co-loading for the prevention of maternal hypotension during elective cesarean section

NCT ID: NCT04404946 Completed - Clinical trials for Cesarean Section Complications

Colloid Co-hydration and Vasoconstrictor Infusion for Prevention of Hypotension During Cesarean Section

annie-zoe
Start date: May 23, 2020
Phase: N/A
Study type: Interventional

This will be a double-blind randomized study, aiming at investigating a fixed rate phenylephrine infusion versus a fixed rate norepinephrine infusion versus placebo in combination with co-hydration with colloids for the prevention of maternal hypotension in elective cesarean section

NCT ID: NCT04401345 Completed - Clinical trials for Hemodynamic Instability

Effect of Glycopyrrolate on Vasopressors Requirement for Non-elective Caesarean Section Under Spinal Anaesthesia

Start date: June 1, 2020
Phase: Phase 4
Study type: Interventional

This is prospective randomised double blind study conducted in parturients planned for non-elective caesarean section under spinal anaesthesia. Glycopyrrolate group will receive 0.2 mg of Glycopyrrolate before start of phenylephrine infusion. Control group will receive 0.2 ml of Normal Saline before start of phenylephrine infusion. Total amount of vasopressors required i.e. ephedrine or phenylephrine will recorded in the form of phenylephrine equivalent during intraoperative period.

NCT ID: NCT04396548 Completed - Clinical trials for Hypotension After Spinal Anesthesia

Midodrine for Improving Hemodynamics After Spinal Anesthesia

Start date: June 8, 2020
Phase: N/A
Study type: Interventional

Neuraxial blockade such as spinal anaesthesia can cause severe hypotension due to pharmacological sympathectomy resulting in potential deleterious consequences for the patient. Prevention of this spinal anaesthesia induced hypotension is of utmost importance. Techniques currently in use for preventing hypotension include intravenous fluid prehydration, sympathomimetic drugs, and physical methods such as leg bindings and compression stockings. Midodrine is a direct acting α1-adrenoceptor agonist which causes venous and arterial vasoconstriction through stimulation of α1- receptors located in the vasculature. The aim of this study is to evaluate the efficacy and safety of prophylactic midodrine use with preoperative fluid hydration before spinal anesthesia in the prevention of hypotension in patients undergoing elective orthopedic surgery. We hypothesize that intraoperative hypotension would be less in patients given midodrine and intravenous fluid prehydration preoperatively before spinal anesthesia.

NCT ID: NCT04367103 Completed - Hypotension Clinical Trials

Norepinephrine for Hypotension in Cesarean Section

Start date: April 10, 2021
Phase: N/A
Study type: Interventional

Hypotension is a very common consequence of the sympathetic vasomotor block caused by spinal anesthesia for cesarean section. Maternal symptoms such as nausea, vomiting and dyspnea frequently accompany severe hypotension, and adverse effects on the fetus, including depressed APGAR scores and umbilical acidosis, have been correlated with severity and duration of hypotension. Because hypotension is frequent, vasopressors should be used routinely and preferably prophylactically.

NCT ID: NCT04320823 Completed - Clinical trials for Apheresis Related Hypotension

IMPACT (Improving Plasma Collection) Clinical Trial

IMPACT
Start date: January 6, 2020
Phase: N/A
Study type: Interventional

Prospective, multi-center, randomized, controlled clinical trial to study the safety and effectiveness of a novel plasma collection system software.