Hypotension on Induction Clinical Trial
Official title:
Mean Arterial Pressure Reduction During the First Ten Minutes After General Anesthesia Induction Using Propofol Bolus or Tritiated Target-infusion: Superiority Randomized Controlled Trial
To compare haemodynamics and bispectral index values between conventional bolus propofol induction and target-controlled propofol infusion.
Status | Not yet recruiting |
Enrollment | 120 |
Est. completion date | November 27, 2020 |
Est. primary completion date | September 25, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 65 Years |
Eligibility |
Inclusion Criteria: - Scheduled for general anesthesia; - No contraindication for propofol. Exclusion Criteria: - Data loss; - Protocol violation. |
Country | Name | City | State |
---|---|---|---|
Brazil | Hospital Universitário de Brasilia | Brasilia | Distrito Federal |
Lead Sponsor | Collaborator |
---|---|
Brasilia University Hospital |
Brazil,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Mean arterial pressure after 2 minutes | Mean arterial pressure using non-invasive device | 2 minutes after general anesthesia induction | |
Primary | Mean arterial pressure after 4 minutes | Mean arterial pressure using non-invasive device | 4 minutes after general anesthesia induction minutes after general anesthesia induction | |
Primary | Mean arterial pressure after 6 minutes | Mean arterial pressure using non-invasive device | 6 minutes after general anesthesia induction minutes after general anesthesia induction | |
Primary | Mean arterial pressure after 8 minutes | Mean arterial pressure using non-invasive device | 8 minutes after general anesthesia induction minutes after general anesthesia induction | |
Primary | Mean arterial pressure after 10 minutes | Mean arterial pressure using non-invasive device | 10 minutes after general anesthesia induction minutes after general anesthesia induction | |
Secondary | Heart Rate after 2 minutes | Heart rate (pulse rate) using non-invasive device. | 2 minutes after general anesthesia induction | |
Secondary | Heart Rate after 4 minutes | Heart rate (pulse rate) using non-invasive device. | 4 minutes after general anesthesia induction | |
Secondary | Heart Rate after 6 minutes | Heart rate (pulse rate) using non-invasive device. | 6 minutes after general anesthesia induction | |
Secondary | Heart Rate after 8 minutes | Heart rate (pulse rate) using non-invasive device. | 8 minutes after general anesthesia induction | |
Secondary | Heart Rate after 10 minutes | Heart rate (pulse rate) using non-invasive device. | 10 minutes after general anesthesia induction | |
Secondary | Bispectral Index after 2 minutes | Bispectral Index (BIS) using non-invasive device. At values near 100 mean patient is more likely to be awake and at values below 60 are more likely to be under general anesthesia. | 2 minutes after general anesthesia induction | |
Secondary | Bispectral Index after 4 minutes | Bispectral Index (BIS) using non-invasive device. At values near 100 mean patient is more likely to be awake and at values below 60 are more likely to be under general anesthesia. | 4 minutes after general anesthesia induction | |
Secondary | Bispectral Index after 6 minutes | Bispectral Index (BIS) using non-invasive device. At values near 100 mean patient is more likely to be awake and at values below 60 are more likely to be under general anesthesia. | 6 minutes after general anesthesia induction | |
Secondary | Bispectral Index after 8 minutes | Bispectral Index (BIS) using non-invasive device. At values near 100 mean patient is more likely to be awake and at values below 60 are more likely to be under general anesthesia. | 8 minutes after general anesthesia induction | |
Secondary | Bispectral Index after 10 minutes | Bispectral Index (BIS) using non-invasive device. At values near 100 mean patient is more likely to be awake and at values below 60 are more likely to be under general anesthesia. | 10 minutes after general anesthesia induction |
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