Remifentanil and Nitroprusside for Controlled Hypotension

Hypotension, Controlled Clinical Trial

Official title:

The Comparison of the Cardiovascular Effects of Remifentanil and Nitroprusside for Controlled Hypotension

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02001298
• Other study ID #: HJKim3
• Status: Completed
• Phase: N/A
• First received: November 24, 2013
• Last updated: December 3, 2013
• Start date: June 2012

Study information

• Verified date: November 2013
• Source: Jeju National University School of Medicine
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is the comparison of the cardiovascular effects of remifentanil and nitroprusside for controlled hypotension

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. primary completion date: July 2013
• Accepts healthy volunteers: No
• Gender: All
• Age group: 20 Years to 60 Years

Eligibility

Inclusion Criteria:

• Patients who underwent endoscopic sinus surgery

Exclusion Criteria:

• patient who took any drug to influence this study

• patient with cardiovascular disease, renal disease or liver disease

Related Conditions & MeSH terms

• Hypotension
• Hypotension, Controlled

Intervention

Drug:
• remifentanil

• nitroprusside

Locations

Country	Name	City	State
Korea, Republic of	Jeju National University Hospital	Jeju-si	Jeju Special Self-Governing Province

Sponsors (1)

Lead Sponsor	Collaborator
Jeju National University School of Medicine

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Stroke volume index	Stroke volume index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of stroke volume index during controlled hypotension was compared with baseline value.	Stroke volume index was continuously measured during controlled hypotension, an average of 90 min
Primary	Cardiac index	Cardiac index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of cardiac index during controlled hypotension was compared with baseline value.	Cardiac index was continuously measured during controlled hypotension, an average of 90 min
Secondary	Total peripheral resistance index	Total peripheral resistance index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of total peripheral resistance index during controlled hypotension was compared with baseline value.	Total peripheral resistance index was continuously measured during controlled hypotension, an average of 90 min