The Role of "Hypospadias Objective Scoring Evaluation" (HOSE) &

Status Recruiting

Clinical Trial Summary

Hypospadias is a common anomaly of the male genitalia affecting 0.4-8.2 of 1000 live male babies and varies considerably in severity. The position of the urethral meatus can be classified as anterior or distal (glandular, coronal, or subcoronal; 60-65% of cases), middle (midpenile; 20-30% of cases), or posterior or proximal (posterior penile, penoscrotal, scrotal, or perineal; 10-15% of cases). The subcoronal position is the most common. Most cases are mild and surgical correction is undertaken mostly for cosmetic reasons at the request of the parents or on advice of the pediatrician or surgeon. Functional success of hypospadias repair depends on the creation of a uniform and adequate caliber urethra up to the meatus. Accordingly, meatal stenosis and urethral stricture are the important complications of surgery, others include urethrocutaneous fistula, diverticula, skin flap necrosis and persistent chordee. Although functional assessment of the repair is possible by observation of the urinary stream and voiding cystourethrography, uroflowmetry is considered to be a more objective tool, especially for the detection of a subclinical urethral stricture. Reports of the results of hypospadias surgery commonly focus on the cosmetic results and incidence of obvious complications, as urethrocutaneous fistulas, and symptomatic urethral Strictures. Few have emphasized the role of uroflowmetry in the postoperative evaluation of children with hypospadias to detect asymptomatic strictures and, despite the simplicity and non-invasive nature of this test, it has not become standard or widely accepted. We evaluate AUUH experience by use of 'hypospadias objective scoring evaluation' HOSE and uroflowmetry after hypospadias repair. The HOSE is a validated scoring system that incorporates the evaluation of meatal location and shape, urinary stream, straightness of erection, presence and complexity of urethral fistula. The minimum total score is 5, and the maximum total score is 16. The point score is graded as either acceptable or not.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Hypospadias

Clinical Trial Details

NCT number	NCT05032222
Study type	Observational [Patient Registry]
Source	Assiut University
Contact	Mohamad A Ezzat, Resident
Phone	+201125035035
Email	mohamed.20134296@med.au.edu.eg
Status	Recruiting
Phase
Start date	May 1, 2021
Completion date	May 1, 2023

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See also
Status	Clinical Trial	Phase
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Completed	`NCT04239066` - Penile Ischemia for Hypospadias Repair and The Patients and Surgeons Reported Outcomes	N/A
Not yet recruiting	`NCT03698721` - Urothelium Tissue Engineering Using Biopsies From Transurethral Resection of Prostate
Completed	`NCT03677453` - Interactive Perioperative Teaching Platform (IPTP)	N/A
Terminated	`NCT04826484` - Opioid Reduction Initiative During Outpatient Pediatric Urologic Procedures Using Exparel	Phase 3
Completed	`NCT02103712` - Long Term Outcome of Hypospadias Repair
Suspended	`NCT05093166` - Clinical Trial to Assess the Safety and Efficacy of Investigational Product in Patients Due to Hypospadias Treatment Failure	Phase 1/Phase 2
Withdrawn	`NCT01762007` - The Change of the Detrusor Thickness After Hypospadias Repair - Comparison With the Normal Control Group
Not yet recruiting	`NCT05569863` - Identification of Hypospadias Parameters Using Digital Photography and Artificial Intelligence
Completed	`NCT02495090` - Hypospadias and Exome: Identification of New Genes for Familial Hypospadias	N/A
Completed	`NCT04668183` - Ultrasound-guided PNB and DPNB for Pediatric Distal Hypospadias Surgery
Completed	`NCT01370798` - Local Oestrogen Versus Placebo as Preoperative Treatment in Patients With Severe Hypospadias: Effects on Post-operative Complications	Phase 3
Recruiting	`NCT06417060` - Caudal Anesthesia Versus Local Anesthesia in Hypospadias	N/A
Active, not recruiting	`NCT02861950` - Does Caudal Block Increase the Incidence of Urethrocutaneous Fistula Formation Following Hypospadias Repair in Infants?	Phase 4
Not yet recruiting	`NCT06410482` - Analgesia in Pediatric Hypospadias Surgeries	N/A
Terminated	`NCT02162810` - Effect of Steroids on Post-Operative Complications Following Proximal Hypospadias Repair	N/A
Recruiting	`NCT05837000` - Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias Repair	Phase 4
Recruiting	`NCT05319782` - Long-term Assesment of Patients Operated for Hypospadias in Their Childhood : Urinary, Aesthetical, Sexual and Psycho-social Consequences	N/A
Completed	`NCT05144659` - Evaluation of Double Faced Transverse Preputial Onlay Island Flap for Hypospadias Repair in Pediatrics	N/A
Suspended	`NCT05708989` - Caudal vs. Pudendal Block in Peds GU	Phase 4

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

The Role of "Hypospadias Objective Scoring Evaluation" (HOSE) and Uroflowmetry in Evaluation of Successful Hypospadias Repair

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms