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Hypopnea Syndrome clinical trials

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NCT ID: NCT04606693 Recruiting - Clinical trials for Atrial Fibrillation, Persistent

Value of Screening and Treatment of SAHS in the Management of AF Ablation Candidates

SLEEP-AF
Start date: November 5, 2020
Phase: N/A
Study type: Interventional

The present prospective cohort study (not randomized) analyses the value of screening and treatment of SAHS in the management of patients with AF refractory to antiarrhythmics drugs, potentially candidates for ablation. Patients at low risk of suffering from SAHS will follow conventional management of their AF, according to the usual criteria of the Arrhythmia Unit. Patients with high or intermediate risk of SAHS, will undergo respiratory polygraphy. If the result is positive, they will be treated as standard for this syndrome and their heart rate will be monitored for 3 months. After this, the patient's arrhythmic load will be reevaluated differentiating patients into two groups, those that must be ablated from those that have improved their condition and the clinical criteria is no longer ablation but follow-up.

NCT ID: NCT04577937 Recruiting - Sleep Disorder Clinical Trials

Sleep Patterns in Patients Affected by Lymphangioleiomiomatosis

Start date: June 30, 2020
Phase: N/A
Study type: Interventional

Lymphangioleiomyomatosis (LAM) is a rare and progressive pulmonary disease of unknown etiology that almost exclusively affects women. It is characterised by cystic radiological lung pattern and by the possible presence of angiomyolipomas in other sites or organs. Functionally LAM is associated with airway obstruction or restriction and progressive hypoxemia up to chronic respiratory failure. There are no studies, so far, which have investigated whether during sleep these patients show changes in the sleep profile and gas exchange and if these changes are related to disease severity. Aim of the study, prospective and pilot, is to evaluate whether the physiological modification of respiratory mechanics during sleep is associated with polysomnographic alterations in LAM.