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Hypopharyngeal Carcinoma clinical trials

View clinical trials related to Hypopharyngeal Carcinoma.

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NCT ID: NCT05494190 Recruiting - Clinical trials for Hypopharyngeal Carcinoma

The Management of Metastatic Neck Nodes in N2/3 Hypopharyngeal Squamous Cell Carcinoma

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

This is a multi-center, multidisciplinary, open-label, randomized controlled prospective clinical study.

NCT ID: NCT05075980 Recruiting - Clinical trials for Head and Neck Carcinoma

HEADLIGHT: Hypofractionated Proton Therapy for Head and Neck Cancers

Start date: February 16, 2022
Phase: Phase 2
Study type: Interventional

This clinical trial tests whether intensity modulated proton therapy after surgery works to shrink tumors in patients with head and neck cancer. Radiation therapy uses high energy protons to kill tumor cells and shrink tumors.

NCT ID: NCT04788264 Completed - Lung Carcinoma Clinical Trials

Exercise Training and Behavioral Modification for the Improvement of Physical Activity in Head and Neck Cancer Patients Undergoing Cancer Treatment

Start date: March 28, 2021
Phase: N/A
Study type: Interventional

This clinical trial evaluates the tolerability of a physical activity program in head and neck cancer patients who are undergoing cancer treatment. The goal of this trial is to give patients exercises prescribed by a physical therapist that they are able to complete regularly at home. Increasing physical activity may help patients reduce fatigue, improve mood, increase physical performance, and decrease joint pain.

NCT ID: NCT04156698 Active, not recruiting - Immunotherapy Clinical Trials

Induction Chemotherapy Combined With Immunotherapy for Locally Advanced Hypopharyngeal Carcinoma

Start date: May 21, 2020
Phase: Phase 2
Study type: Interventional

This is a single-center, multidisciplinary, open-label, single-arm prospective clinical study.

NCT ID: NCT03367884 Not yet recruiting - Clinical trials for Hypopharyngeal Carcinoma

Neck Dissection vs Radiotherapy for Cervical Metastases in Advanced Hypopharyngeal Cancer

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

At the time of diagnosis, approximately 60%-80% of patients with hypopharyngeal cancer are found with cervical lymph node metastasis. Cervical nodal metastasis is an important prognostic factor in hypopharyngeal cancer. Induction chemotherapy is frequently used in advanced hypopharynx cancer. However, sometimes CR was obtained at the tumor's primary site but not in the palpable lymph nodes in the neck, the large cervical lymph node metastasis poorly responded to induction chemotherapy in a considerable percentage of patients. At present, patients with primary tumor achieved CR preferred to receive definitive radiotherapy no matter cervical lymph node metastasis SD or progression. But, radiotherapy was poor effective to the big cervical lymph node metastasis, because the inner of big cervical lymph node metastasis was hypoxic and necrosis. The investigators conducted a prospective, randomised trial to compare neck dissection with definitive radiotherapy for advanced hypopharyngeal cancer cervical lymph node metastasis with poor response to induction chemotherapy.

NCT ID: NCT03132727 Completed - Laryngeal Carcinoma Clinical Trials

Interest of MRI in Preoperative Staging for the Laryngeal and Hypopharyngeal Cancer

Larynx MRI
Start date: March 23, 2017
Phase:
Study type: Observational

To determine if MRI can detect preoperative invasion of cartilage by laryngeal and hypopharyngeal carcinoma, and to compare it to CT imaging and histopathology in excised larynges and/or hypopharynges.

NCT ID: NCT02062632 Terminated - Lymphoma Clinical Trials

Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy

Start date: April 14, 2014
Phase: Phase 2
Study type: Interventional

This randomized pilot clinical trial studies the effects of taking doxepin hydrochloride as compared to placebo (inactive drug) in treating esophageal pain in patients with cancer located in the chest area receiving radiation therapy to the thorax with or without chemotherapy. Doxepin hydrochloride is a tricyclic antidepressant drug which was recently shown to be helpful for mouth pain in patients receiving radiation therapy. Doxepin hydrochloride affects the surface of the esophagus, which may be helpful in reducing the pain caused by radiation therapy.