Hypopharyngeal Cancer Clinical Trial
Official title:
Concurrent Chemoradiation Versus Induction Docetaxel, Cisplatin and 5-fluorouracil (TPF) Followed by Concomitant Chemoradiotherapy in Locally Advanced Hypopharyngeal and Base of Tongue Cancer: A Randomized Phase II Study
The investigators will examine whether 2-cycles of DFP chemotherapy before definitive concurrent chemoradiation therapy (CCRT) can improve progression-free survival in locally advanced (Stage III & IVM0) hypopharyngeal and base of tongue carcinoma compared to definitive CCRT alone.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT02113878 -
Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck
|
Phase 1 | |
Recruiting |
NCT03558035 -
New Strategy of Improving Treatment Outcome and Larynx-preservation Rate in Locally Advanced Hypopharyngeal Carcinoma
|
Phase 2 | |
Completed |
NCT01435252 -
A Phase II Study In Patients With Advanced Head And Neck Cancer Of Standard Chemoradiation And Add-On Cetuximab
|
Phase 2 | |
Recruiting |
NCT04539600 -
Induction Chemotherapy Combined With Camrelizumab in Locoregionally Advanced Hypopharyngeal Cancer
|
Phase 2 | |
Recruiting |
NCT02012699 -
Integrated Cancer Repository for Cancer Research
|
||
Recruiting |
NCT05375266 -
Immune Biomarker Study for Head and Neck Cancer
|
||
Completed |
NCT03934294 -
Acupuncture Effect on Digestion in Critically Ill Post-Operative Oral and Hypo-pharyngeal Cancer Patients
|
N/A | |
Recruiting |
NCT01516996 -
Safety and Efficacy Study of Nimotuzumab Plus Neoadjuvant and Concurrent Chemoradiotherapy to Treat Oropharynx and Hypopharynx Cancer
|
Phase 2 | |
Withdrawn |
NCT01175499 -
Concordance of Two Endoscopic Procedures for Diagnosis of Carcinoma of the Upper Aerodigestive Tract
|
N/A | |
Recruiting |
NCT05860335 -
Efficacy and Safety of Toripalimab Combined With AP-induced Chemotherapy Followed in Non-metastatic IVB Hypopharyngeal Cancer
|
Phase 2 | |
Completed |
NCT00473564 -
Robotic Assisted Surgery in Upper Aerodigestive Tract Surgery
|
N/A | |
Recruiting |
NCT06039631 -
Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer
|
Phase 2 | |
Not yet recruiting |
NCT00302562 -
The Role of MMPs in the CXCL12-Induced Invasion of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma
|
N/A | |
Recruiting |
NCT00174096 -
The Role of Stromal Cell-Derived Factor-1 (SDF-1)/CXC Chemokine Receptor 4 (CXCR4) in Metastasis of Laryngeal and Hypopharyngeal Squamous Cell Carcinoma
|
N/A | |
Recruiting |
NCT00173381 -
The Role of Lymphangiogenesis in Head and Neck Cancer Metastasis
|
N/A | |
Recruiting |
NCT05894070 -
The Voice as a Tool to Detect Recurrence of Laryngeal and Hypopharyngeal Cancer
|
||
Recruiting |
NCT04502641 -
Induction Chemotherapy in Locally Advanced Hypopharyngeal Carcinoma: a Randomised Phase 3 Trial
|
Phase 3 | |
Recruiting |
NCT05420597 -
Induction Chemotherapy and Toripalimab Followed by Radiotherapy in Unresectable Laryngeal/Hypopharyngeal Carcinoma
|
Phase 2 |