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Use of NPSP558 in the Treatment of Hypoparathyroidism — REPLACE  

Hypoparathyroidism Clinical Trial

Official title:
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Investigate the Use of NPSP558, a Recombinant Human Parathyroid Hormone (rhPTH[1-84]) for the Treatment of Adults With Hypoparathyroidism

Clinical Trial Summary

Use of PTH (1-84) a recombinant hormone in escalating doses for the treatment of adults with hypoparathyroidism. The use of PTH should result in a decrease of calcium and vitamin D supplements.

Clinical Trial Description

Patients with a history of hypoparathyroidism will be randomized to receive placebo or study drug for 24 weeks, which will be injected daily in either thigh. During that time they will be monitored for safety (specifically, calcium levels in the blood and urine). In addition, the patients' intake of Vitamin D and calcium will be measured. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00732615
Study type Interventional
Source Takeda
Contact
Status Completed
Phase Phase 3
Start date December 18, 2008
Completion date September 28, 2011
View Details
See also
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