Subclassification of the Syndrome of Inappropriate ADH Secretion

Status Completed

Clinical Trial Summary

The aim of this study is to evaluate the different types of osmotic dysregulation in patients with Syndrome of Inappropriate ADH (SIADH) and, hence, to analyze the pathophysiology of SIADH.

These types will be characterized by measurement of AVP and copeptin while performing an osmotic stimulation with infusion of hypertonic saline.

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01341665
Study type	Observational
Source	University of Wuerzburg
Contact
Status	Completed
Phase	N/A
Start date	March 2008
Completion date	April 2011

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06037928` - Plasma Sodium and Sodium Administration in the ICU
Recruiting	`NCT04561531` - Efficacy and Safety of Bolus Comparing With Continuous Drip of 3% NaCl in Patients With Severe Symptomatic Hyponatremia.	N/A
Terminated	`NCT02012959` - Study of the Safety and Effectiveness of SAMSCA® (Tolvaptan) in Children and Adolescents With Euvolemic or Hypervolemic Hyponatremia	Phase 3
Recruiting	`NCT02936167` - Comparison of Ringer Lactate and Isotonic Acetate Solution as Perioperative Maintenance Fluid for Children	N/A
Completed	`NCT00621348` - Maintenance Intravenous Fluids in Children	Phase 3
Terminated	`NCT03703713` - Colloid Osmotic Pressure and Osmolality in Hyponatremia
Completed	`NCT02926989` - Intravenous Fluids in Hospitalised Children	Phase 4
Terminated	`NCT02959411` - Tolvaptan for Advanced or Refractory Heart Failure	Phase 4
Completed	`NCT02573077` - An Observational Study Measuring Outcomes in Cancer Patients Treated for Moderate to Severe Hyponatremia in Italy
Withdrawn	`NCT02667977` - Reexamining Hypotonic Intravenous Fluid Use	N/A
Terminated	`NCT01708811` - Hyponatremia and Myometrium Contractility. An Invitro Study	N/A
Completed	`NCT01456533` - Copeptin in the Differential Diagnosis of Dysnatremia in Hospitalized Patients	N/A
Withdrawn	`NCT01326429` - Frequency and Origin of Dysnatremias in the Emergency Department	N/A
Terminated	`NCT01227512` - Effects of Tolvaptan vs Fluid Restriction in Hospitalized Subjects With Dilutional Hyponatremia	Phase 3
Recruiting	`NCT06013800` - Hyponatremia Volume Status Analysis by Point-of-care Ultrasound
Terminated	`NCT04020926` - Impact of Hyponatremia on Muscle Strength, Gait and Cognitive Function
Completed	`NCT02545101` - An Observational Study on Real-world Use and Outcomes of Patients Treated With Tolvaptan for Hyponatraemia Due to SIADH	N/A
Withdrawn	`NCT02442674` - A Trial of Tolvaptan in Children and Adolescent Subjects With Euvolemic and Hypervolemic Hyponatremia	Phase 3
Terminated	`NCT02215148` - Pharmacokinetics and Clinical Response of Tolvaptan in Neurocritical Care Patients	N/A
Recruiting	`NCT01748331` - The Effect of Fluid Restriction in Congestive Heart Failure Complicated With Hyponatremia	N/A