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Assessing the Efficacy of Clomiphene Citrate in Patients With Azoospermia and Hypoandrogenism

Hypogonadism Clinical Trial

Official title:
A Randomized, Double-blind, Placebo-controlled Trial of Clomiphene Citrate of Clomiphene Citrate in Hypoandrogenism and Azoospermia

Clinical Trial Summary

Hypothesis: Prescribed clomiphene citrate to azoospermic patients with hypoandrogenism could improve the sperm retrieval in either fresh sperm or after surgical sperm extraction.

Clinical Trial Description

Hypogonadism (low testosterone level) is frequently observed in men presenting with non obstructive azoospermia. Controversy exists regarding the efficacy of preoperative hormonal manipulation in patients with hypogonadism. However, it is possible that hormonal therapy increases intra-testicular testosterone levels, and with a rise in serum testosterone, sperm production and surgical success with microTESE improve. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02137265
Study type Interventional
Source University of Illinois at Chicago
Contact
Status Withdrawn
Phase N/A
Start date September 2015
Completion date October 2020
View Details
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