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Hypoglycemia and the Gut Microbiome

Hypoglycemia Clinical Trial

Official title:
Hypoglycemia and the Gut Microbiome

Clinical Trial Summary

This study is designed to evaluate individuals who are currently experiencing symptoms of hypoglycemia, in order to discern correlations between microbiome composition and patterns of postprandial glycemia.

Clinical Trial Description

Recent studies have shown that analysis of the gastrointestinal microbiome can be used to predict glycemic response to dietary intake. Specifically, integrative analysis of dietary consumption, anthropometrics, physical activity and gut microbiota composition can be used to predict postprandial glycemic excursions. The investigators hypothesize that individualized assessment of glycemic responses to food, together with analysis of the gut microbiome, will allow the design of a personalized dietary approach to minimize glycemic excursions for patients with post-bariatric and other forms of largely postprandial hypoglycemia. Identification of factors predictive of glycemic excursions and subsequent hypoglycemia may ultimately allow individuals to tailor their diet towards foods which would not induce hypersecretion of insulin and subsequent hypoglycemia. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03385707
Study type Observational
Source Joslin Diabetes Center
Contact Mary E Patti, MD
Phone (617) 309-2635
Email maryelizabeth.patti@joslin.harvard.edu
Status Recruiting
Phase
Start date February 7, 2019
Completion date September 2024
View Details
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