Hypocalcemia Clinical Trial
Official title:
Effect of Preoperative High-dose Cholecalciferol in Prevention of Post-thyroidectomy Hypocalcaemia : A Randomized Controlled Trial
Hypocalcaemia after thyroidectomy is observed with increasing frequency, often resulting in prolonged hospital stay with increased use of resources, delayed return to work and reduced quality of life. The administration of vitamin D is essential in the therapy of postoperative hypocalcaemia. What has not been examined so far is whether and how routine preoperative cholecalciferol prophylaxis can help to prevent postoperative hypocalcaemia
Status | Recruiting |
Enrollment | 170 |
Est. completion date | December 2024 |
Est. primary completion date | November 2023 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 70 Years |
Eligibility | Inclusion Criteria: - Adult patients (> 18 years) - Scheduled for TT - Thyroid cancer treated with total thyroidectomy without lymph node dissection Exclusion Criteria: - Lack of written consent - Thyroid cancer treated with TT and lymph node dissection - Mediastinal goiter with need for sternotomy - Medication with thiazide diuretics, digitalis or lithium therapy - Previous neck operations or radiation - Preexisting hyperparathyroidism - Chronic kidney failure. |
Country | Name | City | State |
---|---|---|---|
Pakistan | Pak-Emirates Military Hospital | Rawalpindi | Punjab |
Lead Sponsor | Collaborator |
---|---|
Pak Emirates Military Hospital |
Pakistan,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Post-operative hypocalcemia | The primary outcomes measure of this study was postoperative hypocalcemia based on either clinical symptoms or laboratory values. | After 6 months |
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