Hypocalcemia Clinical Trial
Official title:
Profile of Hypocalcemia in Infants and Children Admitted to Assiut University Children Hospital
NCT number | NCT03685877 |
Other study ID # | HCIIC |
Secondary ID | |
Status | Not yet recruiting |
Phase | |
First received | |
Last updated | |
Start date | March 30, 2019 |
Est. completion date | April 1, 2020 |
Hypocalcemia is defined as reduction in the level of the ionized calcium in the blood to less
than 0.95 mmole/ litre.
In some cases it is associated with symptoms such as neuromuscular impairment in the form of
convulsions ,carpopedal spasm,parathesia ,laryngiospasm ,stridor……etc .Calcium circulates in
blood stream in three fractions :protein bound to calcium,primarly to albumen(40%) and in 50%
of the cases calcium is present in the ionized state which is physiologically active (Dias ,c
et a l, 2013) . Symptomatizing hypocalcemia may occur in cases of vitamin D deficiency
rickets (nutritional deficiency in infants less than two years ) .It may also occur in
vitamin D resistant rickets e.g renal rickets because of failure of the kidney to synthesize
1-OH cholecalciferol of the 1-25 di-OH cholecalciferol (the active form of vitamin D).
Status | Not yet recruiting |
Enrollment | 30 |
Est. completion date | April 1, 2020 |
Est. primary completion date | March 30, 2019 |
Accepts healthy volunteers | |
Gender | All |
Age group | 1 Month to 17 Years |
Eligibility |
Inclusion Criteria: - All symptomatizing hypocalcemic cases presenting acutely to the Assiut University Children Hospital with convulsions, carpopedal spasm, stridor, renal symptoms or malabsorption symptoms aged > 1 month to the age of 17 years. Exclusion Criteria: - All neonatal hypocalcemic cases. |
Country | Name | City | State |
---|---|---|---|
n/a |
Lead Sponsor | Collaborator |
---|---|
Assiut University |
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | hypocalcemia in infants and children | Good management of all cases with symptomatizing hypocalcemia admitted at Assiut University Children Hospital based on knowing the exact final diagnosis by knowing the result of the various investigations as indicated | 1YEAR | |
Secondary | pediatric hypocalcemia | Recommendation for Assiut University Children Hospital for providing all the investigation required so that the patient will not need to pay for any of them if they are not done in the inpatient of the pediatric Assiut University Children Hospital at the present time of the research. | 1YEAR |
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