Hyperventilation Clinical Trial
Official title:
CO2 Rebreathing by a Partial Rebreathing Mask as a Treatment of Chronic Idiopathic Hyperventilation - a Pilot Study
Background: Chronic Idiopathic Hyperventilation (CIH) is a form of dysfunctional breathing
which has proven hard to treat effectively. The investigators hypothesised that by
periodically inducing normocapnia over several weeks, it would be possible to raise the
normal resting level/set point of CO2 and achieve a reduction of symptoms.
Methods: Six CIH patients were treated two hours a day for four weeks with a novel breathing
mask. The mask was used to induce normocapnia in these chronically hypocapnic patients.
Capillary blood gases (PcCO2, pH, Standard Base Excess (SBE) etc.) were measured at baseline
and once each week at least three hours after mask use, as well as spirometric values,
breath holding tolerance and hyperventilation symptoms as per the Nijmegen Questionnaire
(NQ),.
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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