High Intensity Resistance Training Combined With Blood Flow Restricted Exercise in Elite Handball Players

Hypertrophy Clinical Trial

Official title:

High Intensity Resistance Training Combined With Blood Flow Restricted Exercise in Elite Handball Players

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04750694
• Other study ID #: VEK ID 74646
• Status: Recruiting
• Phase: N/A
• Start date: November 1, 2020
• Est. completion date: November 1, 2021

Study information

• Verified date: February 2021
• Source: Department of Public Health, Denmark
• Contact: Simon Lønbro, PhD
• Phone: 004521600410
• Email: loenbro[@]ph.au.dk
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Purpose of the study is: to investigate the effects of 8 weeks intervention of high intensity resistance training(HIRT) combined with Blood Flow Restricted Exercise (BFRE) compared to high intensity resistance training alone. Detailed Description: 30 elite handball players will be randomized into 2 groups of 15 participants each. Participants will be evaluated in the week before and the week after an 8-weeks training intervention with 2 weekly sessions. Based on their baseline muscle strength the participants will be randomized into two groups: HIRT-BFRE or HIRT-HIRT. Participants in both groups will perform a full-body training programme of HIRT. After the Full-body programme, Back squat exercise with low intensity and Blood flow restriction will be performed to the HIRT-BFRE group and back squat exercise with high intensity without blood flow restriction will be performed by HIRT-HIRT. Evaluation protocol includes: muscle strength measurement with 1 repetition maximum of Back squat and knee extension, muscle mass with Dual-Energy X-ray absorptiometry, muscle thickness of the thigh with ultra sound measurement, vertical jump height with linear Encoder, sprint performance with 30m sprint time.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 30
• Est. completion date: November 1, 2021
• Est. primary completion date: November 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• Age >= 18 years
• Ds
• Minimum of 2 years of resistance training experience
• >< Two resistance training sessions each week
• >< three handball sessions each week
• No injuries that prevent participants to perform test of maximal muscle strength
• No injuries, that affects the muscle strength or the ability to train

Exclusion Criteria:

• Elevated blood pressure (>140/90)
• Anabolic steroids or prescription-only medical products with know or potential effect on muscle hypertrophy

Related Conditions & MeSH terms

• Hypertrophy

Intervention

Behavioral:
• Resistance training
A full-training programme with high intensity followed by back squat exercise with blood flow restriction. Inflatable cuffs will be placed proximally on both thighs. The cuff pressure will be 50% of individual arterial occlusion pressure and will be maintained during the rest intervals. Participants will perform 30, 15, 15 and 15 repetitions of 30% of 1 Repetition Maximum. Totally 75 repetitions will be performed. 45 seconds rest interval between sets will be given.

Locations

Country	Name	City	State
Denmark	Dept. of Public Health	Aarhus

Sponsors (1)

Lead Sponsor	Collaborator
Department of Public Health, Denmark

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Jump Performance	Change in jump height. Change in vertical jump height (in cm, with Chronojump Linear Encoder Kit). Participants will perform a counter movement jump and jump as high as possible. The jump height will be recorded.	Baseline measurements at week 1 and post intervention at week 10.
Other	Sprint performance	Sprint performance. Change in sprint time (in seconds, with Witt speed gates). Participant will perform a 30-meter sprint on an indoor handball court. The time to perform a 30-meter sprint will be recorded.	Baseline measurements at week 1 and post intervention at week 10.
Primary	Change in Maximal Muscle Strength	Change in 1 RM (repetition maximum) muscle strength in back squat	Baseline measurements at week 1, after four weeks of exercise at week 5 and post intervention at week 10.
Secondary	Change in Lean body mass	Change in lean body mass assessed by Dual Energy X-ray Absorptiometry	Baseline measurements at week 1 and post intervention at week 10.