Egg Consumption and Muscular Adaptations

Hypertrophy Clinical Trial

Official title:

Comparison of Whole Eggs vs. Egg Whites Consumption on Regulatory Myokines, Muscular Strength, Hypertrophy, Power and Body Composition.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04381390
• Other study ID #: 11/27498
• Status: Completed
• Phase: N/A
• Start date: September 10, 2018
• Est. completion date: October 2, 2019

Study information

• Verified date: May 2020
• Source: Marymount University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Eggs may be a viable alternative to various types of supplemental proteins given its similar ratings on various measures of dietary protein quality.

The investigators hypothesis is that whole eggs would create a greater improvement in skeletal regulatory markers, hormonal responses and body composition than egg white ingestion in resistance-trained men.

Description:

The aim of this investigation was to compare the effects of whole egg versus egg white ingestion (daily and after training sessions) during 12 weeks of resistance training on skeletal muscle regulatory markers, hormonal responses and body composition in resistance-trained men. Specific aims of the study are to:

To investigate the extent to which both whole egg and egg white ingestion will improve anabolic factors, fat free mass, fat mass and decrease catabolic markers after 12 weeks of resistance training in resistance-trained men.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 30
• Est. completion date: October 2, 2019
• Est. primary completion date: October 2, 2019
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• performing resistance training at least three times a week for 1 year prior to the start of the study

• not taking any dietary supplements or medications for at least 1 year prior to the start of the study

• no known medical issues

• no alcohol consumption or smoking for at least 1 year prior to the start of the study

• no egg allergy/sensitivity.

Exclusion Criteria:

• non-willingness to continue nutritional or exercise protocols

• participation in exercise other than the prescribed resistance training program

• consumption of dietary supplement (other than egg) during the study period

• Missing more than one resistance training session or post-exercise egg consumption throughout the study period

Related Conditions & MeSH terms

• Hypertrophy

Intervention

Dietary Supplement:
• Whole egg and resistance training
This intervention consisted of whole egg consumption concomitant with 12 weeks of resistance training. Subject ingested three whole eggs per day immediately after resistance training.
• Egg whites and resistance training
This intervention consisted of egg white consumption concomitant with 12 weeks of resistance training. Subject ingested an isonitrogenous quantity of six egg whites per day immediately after resistance training.

Locations

Country	Name	City	State
United States	Marymount University	Arlington	Virginia

Sponsors (2)

Lead Sponsor	Collaborator
Alexei Wong	Tehran University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Circulatory Myokines levels	Fasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentration of myostatin, follistatin, FGF-2, TGF-ß1 and ACVA.	12 weeks
Primary	Circulatory hormone levels	Fasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentrations of testosterone, IGF-1, insulin and cortisol	12 weeks
Primary	Muscle mass	Skeletal muscle mass will be evaluated using computed tomography	12 weeks
Primary	Body fatness	Body fat will be evaluated using bioelectrical impedance	12 weeks
Secondary	Muscular Strength	Using 1 repetition maximum	12 weeks