Hypertrophic Scar Clinical Trial
Official title:
A Phase I/II Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Preliminary Efficacy of STP705 Administered as Intrascar Injection in Adult Patients With Hypertrophic Scars
Adult patients with hypertrophic scars 30 Subjects in Dose Escalation 20 Subjects in Dose Expansion Intrascar injection of STP705 weekly for 4 weeks
An open label study design to evaluate the preliminary efficacy of STP705 in adult patients with hypertrophic scars. The study is divided into 2 stages: 1. Dose Escalation: 30 subjects to be enrolled in this stage with a total of 6 dose groups. 3 subjects will be enrolled in 10ug and 20ug groups and 6 subjects in the subsequent groups of 40ug, 60ug, 80u and 100ug. 2. Dose Expansion:1-2 dose groups will be selected and 20 subjects will be enrolled in each group. ;
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