Hypertrophic or Keloid Scars Clinical Trial
Official title:
Silicone Gel Versus Onion Extract Gel as Prevention for Postsurgical Scars: a Randomized Controlled Trial
Hypertrophic or keloid scars develop for about 39% to 68% of patients after surgery. The
subjective opinion of the patient regarding the scar will often constitute the standard for
judging the success or failure of the procedure. Surgical scars are not only a cosmetic
concern but they can also cause pain, itching, discomfort, contracture, and other functional
impairment. Various treatment options exists for treating hypertrophic scars and keloids,
including intralesional steroid injection, dermabrasion, pressure therapy, surgical excision,
radiotherapy, cryotherapy, pulse dye, and carbon dioxide laser ablation. However, these
treatments often require multiple visits and have limited success. Therefore, prevention and
early recognition of hypertrophic scars and keloids are very important in their management.
Among preventive treatments available, silicone gel and onion extract gel have been marketed
as products to improve the appearance and texture of surgical scars. Despite its popularity,
data demonstrating the efficacy of these gels are lacking. Furthermore, there is no
comparative study of silicone gel and onion extract gel for preventing postsurgical
hypertrophic or keloid scars. The investigators therefore conducted this randomized
controlled trial to compare the efficacy of silicone gel and onion extract gel for the
prevention of postsurgical hypertrophic scars. The investigators also compared patient
compliance and side effect between two topical gels.
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