Taiwan Registry of Hypertrophic Cardiomyopathy (THIC) Research Synopsis

Status Recruiting

Clinical Trial Summary

Hypertrophic cardiomyopathy (HCM) is hallmarked by the presence of left ventricular hypertrophy (LVH) and may present various symptoms including arrhythmia and heart failure. Mutations in the genes related to sarcomeric proteins and metabolic disorders are known causes of HCM. However, it remains required to further explore the prevalence of HCM in the context of Taiwanese' genetic background. Additionally, certain rare diseases that affect the heart, including Fabry disease, cardiac amyloidosis, may present LVH, which makes precise diagnosis among HCM and these diseases more challenging. In this TSOC multi-center registry, we aim to systematically evaluate the clinical, genetic, biochemical features,prevalence, and possible natural course of HCM and relevant rare diseases such as Fabry disease in Taiwan. In the meanwhile, we may also generate the specific "red-flag" signs of Fabry disease in Taiwan.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06381778
Study type	Observational
Source	Far Eastern Memorial Hospital
Contact	Yen-Wen Wu, PhD
Phone	+886289667000
Email	wuyw0502@gmail.com
Status	Recruiting
Phase
Start date	February 6, 2023
Completion date	December 1, 2027

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