Hypertrophic Cardiomyopathy Clinical Trial
Official title:
Assessment of LV Torsion by Tissue Doppler Echocardiography
The purpose of this study is to learn about the twisting or wringing motion of the heartbeat called Left Ventricular Torsion (LV Torsion) which can be seen on ultrasound.
This study is designed to characterize the myocardial torsional behavior in patients with a
variety of cardiac pathologies.
Simple and inexpensive methods for measurement of LV torsion could facilitate more widespread
investigation of LV torsion, which might reveal significant relationships between torsional
alterations and clinical outcomes and eventually lead to routine clinical application.
Recently, Doppler tissue imaging (DTI) has been shown to accurately reflect myocardial
velocity24,25 with better temporal resolution than MRI.26 Investigators hypothesize therefore
that DTI might be used for quantification of LV rotation and torsion of the human heart. The
purpose of the present study was to examine the accuracy of a novel method with DTI for
quantifying the LV torsion in humans and tagged MRI as the reference standard.
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