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Clinical Trial Summary

Excessive diurnal sleepiness is characterized by an incapacity to stay awake, in favour of sleep occurrence. This sleepiness might be secondary to a sleep disorder; when it is not the case, we talk about primary hypersomnia (including narcolepsy and idiopathic hypersomnia). To date, objective measures of sleepiness can only be achieved in laboratory. Subjective techniques as scales and questionnaires are highly sensitive to inter-individual differences and cannot constitute a reliable diagnosis tool of sleepiness. Recent studies suggested that some salivary biomarkers are sensitive to sleep characteristics and thus, may allow the objective and easy evaluation of sleepiness. The objective of the study is to explore the usability of salivary biomarkers (a-amylase and oxalate) as a new non-invasive technique to evaluate sleepiness and to diagnose primary hypersomnia in children. The hypothesis of this study is that there will be a modification of salivary biomarkers concentrations with the variations of diurnal sleepiness.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05183464
Study type Observational
Source Hospices Civils de Lyon
Contact Patricia FRANCO, PU,PH
Phone 04.27.85.60.52
Email [email protected]
Status Not yet recruiting
Phase
Start date April 1, 2022
Completion date April 1, 2025

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