Skin Tests in Cat Allergic Patients With Cat Dander Samples Obtained Before and After Vaccinating the Cat

Hypersensitivity Clinical Trial

Official title:

Evaluation of Skin Prick Tests in Cat Allergic Patients With Cat Dander Samples Obtained Before and After Vaccinating the Cat

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02667379
• Other study ID #: ZU-HypoCat-001
• Status: Completed
• Phase: N/A
• First received: January 20, 2016
• Last updated: May 6, 2016
• Start date: February 2016
• Est. completion date: May 2016

Study information

• Verified date: May 2016
• Source: University of Zurich
• Contact: n/a
• Is FDA regulated: No
• Health authority: Switzerland: Ethikkommission
• Study type: Interventional

Clinical Trial Summary

Determination of allergenicity of cat dander samples obtained before and after vaccinating the cat

Recruitment information / eligibility

• Status: Completed
• Enrollment: 7
• Est. completion date: May 2016
• Est. primary completion date: May 2016
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• Informed Consent as documented by signature (Appendix Informed Consent Form)

• Male or female between 18 years to 65 years

• Confirmed cat allergy (positive skin prick test)

Exclusion Criteria:

• Diseases or medications, influencing the skin tests or impairing the correct conduct and evaluation of the study

• History of anaphylactic reaction

• Pregnancy

• Skin irritations in test area

• Participation in another clinical trial within the last 30 days and during the present study

Study Design

Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Hypersensitivity

Intervention

Other:
• Diagnostic skin testing
14 Skin prick tests on each volar forearm with cat dander samples.

Locations

Country	Name	City	State
Switzerland	University Hospital Zurich, Dept of Dermatology	Zurich	ZH

Sponsors (1)

Lead Sponsor	Collaborator
University of Zurich

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Wheal size of allergic skin reaction in mm² measured 15 minutes after application of test substance	The primary variable will be the wheal size area of the immediate phase reaction in mm² measured after 15 minutes. Determination of the concentration threshold at which no more skin reactivity can be observed.	15 minutes	No