Hyperparathyroidism Clinical Trial
— APACH1Official title:
Interest of the F18-choline as a Second Line of the Tracer for Detection of Parathyroid Adenomas
Verified date | August 2016 |
Source | Centre Francois Baclesse |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The rationale for the proposed pilot study is to investigate the ability of PET-CT with F18-choline to detect and locate the parathyroid adenoma in patients with primary hyperparathyroidism and negative or non-contributory MIBI (Tc-99m sestamibi) and cervical ultrasound, in order to avoid unnecessary bilateral cervical exploration.
Status | Completed |
Enrollment | 28 |
Est. completion date | February 2017 |
Est. primary completion date | February 2017 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Patient aged 18 years or more; - Patient with a primary hyperparathyroidism and witj a negative or non-contriburatory MIBI parathyroid scintigraphy and neck ultrasonography, for which surgical resection is planned; - Confirmation of the diagnosis of primary hyperparathyroidism on laboratory tests - Affiliate to a social security system; - Patient written informed consent. Exclusion Criteria: - Patient deprived of liberty, under guardianship; - Any medical or psychological condition witch could compromise the capacity of the patient to participate in the study; - Pregnant or breastfeeding |
Country | Name | City | State |
---|---|---|---|
France | Centre François Baclesse | Caen | |
France | CHU | Caen |
Lead Sponsor | Collaborator |
---|---|
Centre Francois Baclesse |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Sensitivity (ability to identify and visualize the parathyroid adenoma) | Sensitivity of PET-CT with F18-choline (FCH) to identify and visualize the parathyroid adenoma in patients with primary hyperparathyroidism and negative or non-contributory parathyroid scintigraphy MIBI and cervical ultrasound | Up to 2 months |
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