Clinical Trials Logo
  1. Home
  2. Hyperparathyroidism
  3. NCT00004843

A Randomized Study of Surgery vs No Surgery in Patients With Mild Asymptomatic Primary Hyperparathyroidism

Hyperparathyroidism Clinical Trial

Official title:
A Randomized Study of Surgery vs No Surgery in Patients With Mild Asymptomatic

Clinical Trial Summary

OBJECTIVES: I. Assess the efficacy of surgery vs no surgery in patients with mild asymptomatic primary hyperparathyroidism.

II. Assess the quality of life, morbidity, and mortality of these patients.

Clinical Trial Description

PROTOCOL OUTLINE: This is a randomized, multicenter study. Patients are stratified by gender. Patients are randomized to receive surgery or follow up without surgery.

Patients receive parathyroidectomy (current standard care) or long term follow up without parathyroidectomy.

Quality of life is assessed before the study and then every 6 months. All patients are followed every 6 months until death. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00004843
Study type Interventional
Source National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Contact
Status Completed
Phase N/A
Start date April 1997
Completion date March 30, 1999
View Details
See also
  Status Clinical Trial Phase
Completed NCT00377312 - 7 Day Continuous Parathyroid Hormone IV Infusion Phase 0
Completed NCT00379899 - ADVANCE: Study to Evaluate Cinacalcet Plus Low Dose Vitamin D on Vascular Calcification in Subjects With Chronic Kidney Disease Receiving Hemodialysis Phase 4
Completed NCT04040946 - Trial Comparing 2 Diagnostic Strategies for Preoperative Localization of Parathyroid Adenoma in Primary Hyperparathyroidism:TEMP / CT With Tc99m-sestaMIBI or PET / CT With F18-choline in First Intention Phase 3
Recruiting NCT03053999 - Variables That Are Correlated to Developing Multiple Endocrine Neoplasia (MEN) and Pancreatic Neuroendocrine Tumors (PNET)
Withdrawn NCT02711059 - Insulin Resistance in Primary Hyperparathyroidism N/A
Completed NCT01691781 - The Renin-Angiotensin-Aldosterone System and Parathyroid Hormone Control: The RAAS-PARC Study N/A
Completed NCT00887666 - Pilot Study: Hypovitaminosis D, Hyperparathyroidism and Hypomagnesemia in Patients With Congestive Heart Failure N/A
Completed NCT00538720 - Effects of Vitamin D Replacement in Patients With Primary Hyperparathyroidism (PHPT) Phase 1
Terminated NCT03044600 - Gene Expression in Hyperparathyroidism
Completed NCT03747029 - Serum Calcium to Phosphorous (Ca/P) Ratio in the Diagnosis of Ca-P Metabolism Disorders: a Multicentre Study
Completed NCT01872429 - Short- and Long-Term Impact of Subtotal Parathyroidectomy on the Achievement of Bone and Mineral Parameters Recommended by Clinical Practice Guidelines in Dialysis Patients N/A
Completed NCT00800358 - Safety and Efficacy Study of Paricalcitol Versus Calcitriol in the Treatment of Secondary Hyperparathyroidism N/A
Recruiting NCT00169806 - Randall's Plaque Study: Pathogenesis and Relationship to Nephrolithiasis N/A
Completed NCT03968510 - Swalqol in Primary Hyperparathyroidism
Completed NCT00501215 - Effect of Parathyroidectomy on Sleep N/A
Completed NCT02591160 - Optimal HCTZ Cessation for Diagnosis of Hyperparathyroidism N/A
Recruiting NCT05299632 - F-18 PSMA for Localization of Parathyroid Adenoma
Recruiting NCT02986607 - Corticosteroid Rhythms in Hypoparathyroid Patients Early Phase 1
Completed NCT02432599 - Interest of the F18-choline as a Second Line of the Tracer for Detection of Parathyroid Adenomas Phase 2
Completed NCT02524041 - Association Between Serum Periostin Levels and Cortical Porosity in Patients With Secondary Hyperparathyroidism N/A