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Hyperopia clinical trials

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NCT ID: NCT01556893 Completed - Myopia Clinical Trials

Creating LASIK Flaps With the LenSx Femtosecond Laser

Start date: April 2012
Phase: Phase 1
Study type: Interventional

This will be a prospective, single-center clinical trial of up to 50 eyes of subjects scheduled to undergo LASIK surgery requiring an initial corneal flap. Subjects will be screened for eligibility. Subjects will undergo LASIK surgery using the LenSx Laser to create the corneal flap prior to excimer laser treatment. Subjects will be evaluated intraoperatively to assess the ease of lifting the flaps, the stromal bed quality, and the amount of opaque bubble layer. All patients will be followed with routine vision exams for 3 months postoperatively to evaluate changes in visual acuity, manifest refraction, slit lamp examination, and endothelial cell counts.

NCT ID: NCT01515475 Completed - Hyperopia Clinical Trials

Hyperopia Treatment Study 1 (HTS1) - Glasses vs Observation

HTS1
Start date: February 23, 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to compare visual acuity outcomes and development of strabismus after a 3-year follow-up period in children age 12 to <72 months with moderate hyperopia (spherical equivalent +3.00D to +6.00D) who are prescribed glasses either immediately or only after confirmation of pre-specified deterioration criteria.

NCT ID: NCT01467557 Completed - Myopia Clinical Trials

Daily Disposable Performance of 1•DAY ACUVUE® TruEye™ and 1•DAY ACUVUE® MOIST® With LACREON® TECHNOLOGY

TEMPO
Start date: October 2011
Phase:
Study type: Observational

This study is an observational registry of patients who have recently been prescribed 1•DAY ACUVUE® TruEye® or 1•DAY ACUVUE® MOIST® Brand Contact Lenses with LACREON® TECHNOLOGY.

NCT ID: NCT01392950 Completed - Myopia Clinical Trials

Clinical Study of Clariti Monthly Contact Lens

Start date: September 2010
Phase: N/A
Study type: Interventional

A clinical study report follows; this clinical study evaluated the safety and efficacy of SAUFLON CLARITI Soft Silicone Hydrogel Contact Lens with UV Blocker by comparison with Air Optix Aqua silicone hydrogel contact lenses (Ciba Vision Inc.). Subjects used OptiFree Replenish solution (Alcon Laboratories Inc.) for daily lens maintenance, care and storage.

NCT ID: NCT01387360 Completed - Myopia Clinical Trials

Presbyopic Supracor Treatment for Near Myopic/Hyperopic Pseudophakic Eyes

SUPRACOR
Start date: June 2011
Phase: Phase 4
Study type: Interventional

This clinical study has been planned to determine the effectiveness of a special laser treatment intended to correct both near and distance vision in patients who have undergone previous cataract surgery.

NCT ID: NCT01322919 Completed - Myopia Clinical Trials

Safety and Efficacy Study to Evaluate the Treatment of Both Near and Distance Vision in a Simultaneous Laser Procedure

Supracor
Start date: April 2010
Phase: Phase 3
Study type: Interventional

By using a new software two consecutive laser treatments have been combined to correct the distance vision and to provide a near vision component in addition to the first treatment. This study will help us to answer 2 questions: 1. How accurately this combined technique corrects distance and near vision 2. Whether the correction is adequate to remove the complete need for supplementary near spectacles

NCT ID: NCT01296867 Completed - Myopia Clinical Trials

Corneal Asphericity Adjustment (Q Adjustment) in Myopic and Hyperopic Patients Undergoing Refractive Correction With Excimer Laser

Start date: March 2006
Phase: N/A
Study type: Observational

To study the postoperative results in myopic and hyperopic eyes treated with two different laser ablation algorithms (STD and F-CAT), both FDA approved.

NCT ID: NCT01228591 Completed - Hyperopia Clinical Trials

Pilot Dispensing Evaluation of a Plus Power Lens

Start date: October 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the performance of the ACUVUE® ADVANCE® Plus lenses against ACUVUE® ADVANCE® lenses in the plus power parameters.

NCT ID: NCT01216475 Recruiting - Myopia Clinical Trials

Randomized, Non-inferiority Trial Comparing SMILE and LASIK

Start date: February 2012
Phase: N/A
Study type: Interventional

Background: Small Incision Lenticule Extraction or SMILE is a novel form of 'flapless' corneal refractive surgery that was adapted from Refractive Lenticule Extraction (ReLEx). SMILE uses only one femtosecond laser to complete the refractive surgery, potentially reducing surgical time, side effects and cost. If successful, SMILE could potentially replace the current, widely practiced Laser In-situ Keratomileusis or LASIK. The aim of this study is to evaluate whether SMILE is non-inferior to LASIK in terms of refractive outcomes at 3-months post-operatively. Methods/ Design: Single tertiary center, parallel group, single-blinded, paired-eye design, non-inferiority, randomized controlled trial. Participants who are eligible for LASIK will be enrolled for study after informed consent. Each participant will be randomized to receive SMILE and LASIK in each eye. Our primary hypothesis (stated as null) in this non-inferiority trial would be that SMILE differs from LASIK in adults (>21 years old) with myopia (> -3.00D) at a tertiary eye center in terms of refractive predictability at 3 months post-operatively. Our secondary hypothesis (stated as null) in this non-inferiority trial would be that SMILE differs from LASIK in adults (>21 years old) with myopia (> -3.00D) at a tertiary eye center in terms of other refractive outcomes (efficacy, safety, higher-order aberrations) at 3 months post-operatively. Our primary outcome is refractive predictability, which is one of several standard refractive outcomes, defined as the proportion of eyes achieving a postoperative spherical equivalent (SE) within ±0.50 diopter (D) of the intended target. Randomization will be performed using random allocation sequence generated by a computer with no blocks or restrictions, and implemented by concealing the number-coded surgery within sealed envelopes until just before the procedure. In this single-blinded trial, subjects and their caregivers will be blinded to the assigned treatment in each eye. Discussion: This novel trial will provide information on whether SMILE has comparable, if not superior, refractive outcomes compared to the established LASIK for myopia, thus providing evidence for translation into clinical practice.

NCT ID: NCT01155726 Completed - Myopia Clinical Trials

The Effect of Masking on Subjective Results During Daily Disposable Contact Lens Studies

ARGON
Start date: May 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to explore the effect of masking on subjective ratings for two daily disposable contact lenses.