Clinical Trials Logo

Clinical Trial Summary

This study investigates the differens in sodium storage in skin between normal subjects, patients after cardiac surgery and septic patients.


Clinical Trial Description

According to the current paradigm ICU-acquired hypernatremia is mainly an iatrogenic problem, caused by sodium overload or water deficit. In spite of several interventions to reduce sodium intake and optimize fluid balance, critically ill patients still develop hypernatremia. These patients also seem to have an inability to excrete sodium, hence develop a positive sodium balance. In animals sodium storage in the third compartment was found. Our hypothesis is that sodium storage in the third compartment is different in critically ill patients and this difference could play a role in the development of ICU-acquired hypernatremia. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02912299
Study type Observational
Source Medical Centre Leeuwarden
Contact
Status Completed
Phase N/A
Start date November 3, 2016
Completion date September 5, 2017

See also
  Status Clinical Trial Phase
Recruiting NCT06037928 - Plasma Sodium and Sodium Administration in the ICU
Completed NCT02926989 - Intravenous Fluids in Hospitalised Children Phase 4
Not yet recruiting NCT05085223 - Prospective Analysis Into Development of Hypernatremia in Critically Ill Patients
Withdrawn NCT01326429 - Frequency and Origin of Dysnatremias in the Emergency Department N/A
Completed NCT01456533 - Copeptin in the Differential Diagnosis of Dysnatremia in Hospitalized Patients N/A
Recruiting NCT03658850 - Safety and Efficacy of Hydrochlorothiazide in the Treatment of Hypernatremia in Critically Ill Patients Phase 2
Not yet recruiting NCT06061783 - Correction of Hypernatremia by Intravenous Hypotonic Solution Compared to Enteral Water N/A
Completed NCT01219179 - Use of Sterile Water Feeds for Treatment of Hypernatremia in Extremely Low Birth Weight Infants N/A
Completed NCT03752450 - Prospective Data Analysis of the Development of Hypernatremia in Intensive Care Unit
Recruiting NCT04949139 - Efficacy and Safety of Rapid Intermittent Correction Compared With Slow Continuous Correction in Patients With Severe Hypernatremia Phase 4
Completed NCT00734214 - Hypotonic Versus Isotonic Parenteral (HIP) Fluid Trial Phase 3
Recruiting NCT02449382 - Continuous Venovenous Hemofiltration Versus Conventional Treatment for Acute Severe Hypernatremia N/A
Withdrawn NCT01617798 - Stop Hypernatremia, Use Metolazone, for Aggressive, Controlled, Effective Diuresis N/A
Recruiting NCT05818826 - Early Versus Conventional Cessation of Hydrocortisone in Septic Shock Phase 2
Recruiting NCT01299428 - Evaluation of the Cerebral Oxygenation With Near Infrared Spectrophotometry (NIRS) at the Hypernatremic Dehydration in Newborn N/A
Recruiting NCT04265976 - ED Hypernatremia. Prognostic Factors and Epidemiology.
Completed NCT03610074 - Relieve the Patient's Thirst, Refresh the Mouth First (ICU-MIC) N/A