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Exercise in Patients With Hypermobile Joints and Knee Pain — HIPEr-Knee  

Knee Discomfort Clinical Trial

Official title:
High-load Resistance Training Compared With Usual Care for Treatment of Painful Knee Joint Hypermobility in Young Adults: A Randomised Controlled Trial (the HIPEr-Knee Study)

Clinical Trial Summary

Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving activity-related pain in young patients (18-45 years) with hypermobile joints and knee pain.

Clinical Trial Description

Knee joint hypermobility is common in the adult population. Patients with knee joint hypermobility and knee pain are typically managed with low intensity resistance training and proprioceptive training to reduce knee pain and improve function, but many patients do not respond well to these treatment strategies. High-load resistance training offers additional benefits to low intensity resistance training, including marked increase in muscle cross-sectional area, neural drive, and increased tendon stiffness, all important components of acquiring active knee joint stability during movement tasks and daily life. Therefore, the primary aim of this randomised controlled trial (RCT) is to investigate if high-load resistance training is superior to usual care in reducing activity-related pain in young patients (18-45 years) with hypermobile joints and knee pain. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06277401
Study type Interventional
Source University of Southern Denmark
Contact Behnam Liaghat, PhD
Phone +4526826801
Email bliaghat@health.sdu.dk
Status Recruiting
Phase N/A
Start date February 21, 2024
Completion date June 1, 2026
View Details
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