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Hyperlipoproteinemia Type V clinical trials

View clinical trials related to Hyperlipoproteinemia Type V.

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NCT ID: NCT05088759 Active, not recruiting - ASCVD Clinical Trials

Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density Lipoprotein Management

LDL-ALERT
Start date: October 8, 2021
Phase: N/A
Study type: Interventional

A 400-patient U.S.-based single-center Quality Improvement Initiative in the form of a randomized controlled trial focused on the feasibility of implementation of this electronic alert-based CDS (EPIC BPA) based on LDL-C values. The 400 patients will be comprised of 200 in the "Hospitalized Patient Cohort" and 200 in the "Outpatient Clinic Cohort." The allocation ratio will be 1:1 for an electronic alert-based CDS (EPIC BPA) notification versus no notification.

NCT ID: NCT05085184 Active, not recruiting - Hyperlipemia, Mixed Clinical Trials

Study to Evaluate the Safety and PK of UI018

Start date: September 6, 2021
Phase: Phase 1
Study type: Interventional

This Study is to evaluate the safety and pharmacokinetics of a fixed dose combination formulation and co-administration.

NCT ID: NCT04885218 Completed - Clinical trials for Mixed Hyperlipidemia

Efficacy and Safety of SHR-1209 Combined With Lipid-lowering Agents in Patients With Hypercholesterolemia

Start date: July 30, 2021
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy, safety, pharmacokinetics and immunogenicity of SHR-1209 subcutaneous administration in patients with non-familial hypercholesterolemia and mixed hyperlipidemia after lipid-lowering therapy

NCT ID: NCT04849000 Completed - Clinical trials for Primary Hypercholesterolemia

Study of SHR-1209 in the Treatment of Hypercholesterolemia and Hyperlipidemia Ⅲ Stage

Start date: April 23, 2021
Phase: Phase 3
Study type: Interventional

The study is ongoing to evaluate the efficacy and safety of SHR-1209 in patients with hypercholesterolemia and hyperlipemia.

NCT ID: NCT02069106 Withdrawn - Clinical trials for Mixed Hyperlipoproteinemia

Efficacy Study of Daily Pro-Omega LDL for Low-Density Lipoprotein Cholesterol and Triglyceride Reduction

PrOteCT
Start date: February 2014
Phase: Phase 4
Study type: Interventional

Pro-Omega LDL reduces low-density lipoprotein cholesterol and triglycerides in subjects with mixed hyperlipoproteinemia.

NCT ID: NCT02008084 Completed - Clinical trials for Hypertriglyceridemia

A Pilot Study to Evaluate the Lipid Effects of TRIA-662

Start date: December 2013
Phase: Phase 2
Study type: Interventional

The purpose of this pilot study is to learn what study factors are important in designing a large, full-scale study of the effects of TRIA-662 on serum triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) levels. In this study, patients will first enter a Single-blind, dietary-controlled baseline period and receive 1000 mg placebo or active drug three times daily with meals (i.e., breakfast, lunch, and dinner) for 6 - 8 weeks. If the qualify to continue, they will then receive up to 2000 mg of active or placebo drug for an additional 14 weeks. Active drug will be given to 48 patients and placebo drug will be given to 16 patients. However, neither the patients not the clinic staff will know which patients are on active or placebo drug until the end of the study.

NCT ID: NCT01974297 Recruiting - Clinical trials for Mixed Hyperlipidemia

Comparison of the Efficacy and Safety of AtorVastatin mOnotherapy vs. Combination Atorvastatin/Fenofibric Acid

AVOCADO
Start date: July 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to compare combination atorvastatin/fenofibric acid 10/135mg with atorvastatin 20mg monotherapy in the mixed hyperlipidemia who were not at lipid goals with atorvastatin 10mg monotherapy.

NCT ID: NCT01956201 Recruiting - Clinical trials for Mixed Hyperlipidemia

Efficacy and Safety of Fenofibrate Added on to Atorvastatin Compared With Atorvastatin

Start date: December 2013
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Atorvastatin and Fenofibrate compared with atorvastatin monotherapy in mixed hypercholesterolemic patients.

NCT ID: NCT01012219 Completed - Clinical trials for Primary Hypercholesterolemia

A Study to Evaluate the Effects of Laropiprant on the Antiplatelet Effects of Clopidogrel and Aspirin in Combination (MK-0524A-114)(COMPLETED)

Start date: November 2009
Phase: Phase 1
Study type: Interventional

This is a 3-period study. Periods 1 and 2 will evaluate the effects of multiple doses of laropiprant on the antiplatelet effects of clopidogrel and aspirin administered in combination in participants with primary hypercholesterolemia or mixed dyslipidemia. Period 3 will be open-label and will evaluate single dose pharmacokinetics of nicotinic acid and laropiprant components of Tredaptive.

NCT ID: NCT00941603 Completed - Clinical trials for Primary Hypercholesterolemia

Phase 2 Dose-Ranging Efficacy and Safety Trial of SCH 900271 in Participants With Primary Hypercholesterolemia or Mixed Hyperlipidemia (P05675)

Start date: June 29, 2009
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the effect of SCH 900271 compared to placebo on the reduction of low-density lipoprotein cholesterol (LDL-C) from baseline to 8 weeks of treatment in participants with primary hypercholesterolemia (familial and nonfamilial) or mixed hyperlipidemia. The study will also evaluate the effect of SCH 900271 on non-high density lipoprotein cholesterol (non-HDL-C) and various other lipids and lipoproteins. The safety of SCH 900271 in this participant population will also be evaluated.