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Hyperkinesis clinical trials

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NCT ID: NCT00491647 Completed - Clinical trials for Attention-deficit/Hyperactivity Disorder

Time Perception Deficits and Attention-Deficit/Hyperactivity Disorder

Start date: May 2006
Phase: N/A
Study type: Observational

Background: Literature has documented that children with attention-deficit/ hyperactivity disorder (ADHD) have difficulties in time management by manifesting with difficulties making plans, organizing tasks and activities, and awaiting their turns. However, the studies regarding time perception have been few as compared to those of neuropsychological measures and there is no information about this topic in Chinese population. In view of this, we will conduct a study to investigate the clinical and treatment aspects of time perception among children and adolescent with ADHD. Specific Aims: 1. to examine the developmental and gender effect on the performance in time perception; 2. to explore the deficit in time estimation, time discrimination, and time reproduction in children and adolescents with ADHD as compared to normal controls; 3. to identify the association between ADHD symptoms and performance in time perception tasks; and 4. to investigate the efficacy of MPH on the time perception measures among children and adolescents with ADHD; Subjects and Methods: This protocol consists of two studies. First, we will recruit 100 patients with DSM-IV ADHD, aged 9 to 16 years, and 100 school controls. They and their parents will receive K-SADS-E interviews. All of them will have complete assessments of time estimation, time discrimination, and time reproduction. Their parents also report on SNAP-IV and CPRS-R:S. The 2nd assessments will be performed 3 months later after the subjects received treatment at outpatients. Anticipated Results: We anticipated that the ADHD group will have poorer time perception, particularly in difficult tasks, and the impairment will be reduced after treatment with medication

NCT ID: NCT00486083 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Comparison Atomoxetine Hydrochloride and Comparator in Pediatric Outpatients With ADHD

Start date: December 2003
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare atomoxetine hydrochloride and methylphenidate hydrochloride in pediatric patients with ADHD.

NCT ID: NCT00485875 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Safety and Efficacy of Switching From a Stimulant Medication to Atomoxetine in Children and Adolescents With ADHD

Start date: June 2004
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess changes in ADHD symptoms and tolerability of medication in children and adolescents switching from a stimulant to atomoxetine.

NCT ID: NCT00485797 Completed - Clinical trials for Attention Deficit Disorder With Hyperactivity

Effects of Ritalin on Postural Stability of Hyper Active Children

Start date: October 2007
Phase: N/A
Study type: Interventional

Experimental design overview The proposed project is a prospective experimental study design. Children (age <15) suffer from attention deficit hyperactivity disorder (ADHD) that their Parents willing to participate in the study will be tested with well-established measuring techniques of Balance control before and 1 hour after taking of Methylphenidate (Ritalin) in the movement and Rehabilitation Laboratory at BGU. An automated algorithm will be used to extract standardized stabilogram-diffusion parameters from each of the COP data sets collected during quiet standing. These parameters include diffusion coefficients, critical displacement, critical time and scaling exponents for both lateral and anterior-posterior sway directions (Collins & De Luca, 1993). For each of the conditions (before and 1 hour after the use of Ritalin) in three task conditions single task; dual task (concentrating and identifying specific music); and just Listening to a relaxing music. Participants will be required to stand on the platform 10 times for 30 s. For each trial, they will be instructed to sway as little as possible.

NCT ID: NCT00485628 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Safety Study in Outpatient Japanese Children With ADHD

Start date: April 2003
Phase: Phase 2
Study type: Interventional

Evaluate the safety and efficacy of atomoxetine in Japanese pediatric patients with ADHD.

NCT ID: NCT00485550 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Comparison of Atomoxetine Plus Either Comparator or Placebo in Children With ADHD Who Haven't Responded to Stimulant Therapy

Start date: January 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of atomoxetine alone versus atomoxetine plus low-dose, sustained-release MPH in children with treatment-resistant ADHD.

NCT ID: NCT00485459 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Atomoxetine Hydrochloride Versus Placebo in Taiwanese Children and Adolescents With ADHD

Start date: February 2004
Phase: Phase 3
Study type: Interventional

The purpose of this protocol is to investigate the acute treatment efficacy, safety, and tolerability of atomoxetine on a once-daily dosing strategy in Taiwanese children and adolescents with ADHD.

NCT ID: NCT00483106 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Clinical and Pharmacogenetic Study of Attention Deficit With Hyperactivity Disorder (ADHD)

Start date: November 1999
Phase: Phase 4
Study type: Interventional

Attention deficit with hyperactivity disorder (ADHD) is a very common behavioral problem during childhood. It is estimated that up to 80% of this disorder could be related to genetic factors. The most common treatment for ADHD is psychostimulants. In this study, the researchers investigate the effect of genetic variants in increasing the risk for behaviours pertinent to ADHD or in modulating the response of these behaviours to methylphenidate. Response to methylphenidate is evaluated through a double blind placebo controlled one week study.

NCT ID: NCT00482313 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Efficacy and Effectiveness of Methylphenidate in Swedish Male Prison Inmates With Attention-deficit Hyperactivity Disorder (ADHD)

Start date: May 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and effectiveness of methylphenidate in treatment of ADHD in Swedish adult male prison inmates diagnosed with ADHD.

NCT ID: NCT00475735 Completed - Clinical trials for Attention-Deficit/Hyperactivity Disorder (ADHD)

A Study to Test the Safety and Efficacy of MK0249 in Patients With ADHD (0249-018)(COMPLETED)

Start date: July 2007
Phase: Phase 2
Study type: Interventional

The purpose of this study is to investigate the safety and efficacy of an investigational treatment for Attention Deficit Hyperactivity Disorder (ADHD) when compared to placebo.