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Hyperkinesis clinical trials

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NCT ID: NCT03610464 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

Pharmacokinetic Study of DYANAVEL XR (Amphetamine) Extended-release Oral Suspension, in Children Aged 4 to 5 Years

Start date: May 7, 2018
Phase: Phase 4
Study type: Interventional

The objective of this study was to evaluate the plasma amphetamine concentration/time profile of amphetamine extended release oral suspension in children aged 4 to 5 years with attention-deficit/hyperactivity disorder, following a single 2.5 mg dose of amphetamine extended release oral suspension.

NCT ID: NCT03609619 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

PART B: Efficacy and Safety of AEVI-001 in Children and Adolescents With ADHD and Without mGluR Mutations

Start date: August 17, 2018
Phase: Phase 2
Study type: Interventional

This is PART B of a 2-part, 6-week, double-blind, dose-optimization, parallel-group study in children and adolescents (ages 6-17 years) with ADHD with and without CNVs in specific genes implicated in glutamatergic signaling and neuronal activity. PART B will assess subjects who do not have CNVs in any of the specific gene mutation(s) implicated in glutamatergic signaling and neuronal connectivity.

NCT ID: NCT03605849 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

A Trial Evaluating the Long-term Safety and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-Deficit/Hyperactivity Disorder

Start date: February 14, 2019
Phase: Phase 3
Study type: Interventional

This study will evaluate the long-term safety and tolerability of centanafadine sustained-release tablets, administered twice daily in the treatment of adults with attention deficit hyperactivity disorder (ADHD).

NCT ID: NCT03605836 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

A Trial to Evaluate the Efficacy, Safety, and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-deficit/Hyperactivity Disorder

Start date: January 16, 2019
Phase: Phase 3
Study type: Interventional

This study evaluated the efficacy, safety, and tolerability of centanafadine sustained-release tablets in adults with ADHD. Participants either received a twice-daily dose of centanafadine sustained-release tablets, or twice-daily placebo.

NCT ID: NCT03605680 Completed - Clinical trials for Attention Deficit Hyperactivity Disorder

A Trial Evaluating the Efficacy, Safety, & Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-deficit/Hyperactivity Disorder

Start date: January 16, 2019
Phase: Phase 3
Study type: Interventional

This study evaluates the efficacy, safety, and tolerability of centanafadine sustained-release tablets in adults with attention-deficit/hyperactivity disorder (ADHD). Participants will either receive a twice-daily dose of centanafadine sustained-release tablets, or twice-daily placebo.

NCT ID: NCT03601858 Recruiting - Clinical trials for Attention Deficit and Hyperactivity Disorder

Descriptive Epidemiology of a Specialized Consultation on ADHD in Adults at the Strasbourg University Hospital

Stras-TDA
Start date: June 1, 2018
Phase:
Study type: Observational

The main objective of this study is to carry out a descriptive study of the clinical and demographic characteristics of patients having consulted for a specialized opinion about ADHD in adults of the psychiatric service of the Strasbourg University Hospital. The characteristics of patients were collected during the first consultation, by the psychiatrist, and analyzed retrospectively. The secondary objective is to evaluate the evolution at one year in terms of follow-up, maintenance under medical treatment and perceived effects of it. The patients who had a prescription for pharmacological treatment of ADHD were contacted between 9 and 15 months after the first consultation and responded to a questionnaire assessing the evolution.

NCT ID: NCT03597503 Terminated - Clinical trials for Attention Deficit Hyperactivity Disorder

Treatment of Impulsive Aggression (IA) in Adolescent With ADHD in Conjunction With Standard ADHD Treatment

Start date: July 31, 2018
Phase: Phase 3
Study type: Interventional

The purpose of this study was to evaluate the effect of SPN-810 for the treatment of impulsive aggression (IA) in adolescents diagnosed with ADHD when taken in conjunction with standard ADHD treatment.

NCT ID: NCT03595826 Completed - Clinical trials for Attention Deficit Disorder With Hyperactivity

Co Morbid Attention Deficit and Hyperactivity Disorder(ADHD) and Developmental Co Ordination Disorder (DCD)

Start date: May 2, 2018
Phase: N/A
Study type: Interventional

This study aims to establish and present the prevalence figures and demographics of the co-morbidity of ADHD and DCD. It further aims to design an exercise intervention, to be utilised in the management of the symptoms of both conditions. Furthermore, it aims at establishing the efficacy of this exercise intervention, when compared with the current and most commonly used intervention, that is: neurostimulant drugs.

NCT ID: NCT03580005 Withdrawn - Clinical trials for Attention Deficit Hyperactivity Disorder

A 6-week Study to Evaluate the Safety and Efficacy of Quillichew ERCT in 4-5 Year Old Children With ADHD.

Start date: October 31, 2018
Phase: Phase 4
Study type: Interventional

A 6-week double-blind study to evaluate the safety and efficacy of Quillichew extended release chewable tablets in 4-5 year old children with attention deficit hyperactivity disorder.

NCT ID: NCT03565250 Recruiting - Clinical trials for Attention Deficit Hyperactivity Disorder

A Study of Identity Building in Children With ADHD

SID-ADHD
Start date: July 20, 2018
Phase: N/A
Study type: Interventional

Context: Attention Deficit Hyperactivity Disorder (ADHD), a major public health issue, is a neurodevelopmental disorder characterized by disturbance of attention, pathological impulsivity and a variable level of psychomotor hyperactivity. In addition to medium-term repercussions such as school failure or family dysfunction, these children have difficulties in dealing with emotions, metacognition and self-awareness that have serious consequences for self-regulation and identity construction. Objective: To investigate identity building in children with ADHD and explore its links with the severity of the disorder and associated neuropsychological disturbances. Material and method: 20 childrens with ADHD and 20 controls will be recruited over a 24-month period. They will be administered the Damon and Hart's Self-Understanding Interview, exploring 7 identity domains: Physical, Active, Social, Psychological, Continuity, Agentivity, Distinction Self/Other. The severity of ADHD, neuropsychological functioning (attention, working memory, executive functions, long-term memory), self-esteem and internal/external attributive style (locus of control) will be assessed by validated scales. The overall level of identity development and in each dimension will be compared between patients and controls. Within patients, the correlations between level of identity development and the severity of ADHD will be explored, as well as with neuropsychological functioning, with statistical control of age. Assumptions: The investigators hypothesize that children with ADHD will exhibit a significantly lower level of identity development than controls, which will be positively correlated with neuropsychological functioning, and negatively correlated with the severity of ADHD.