Hypercholesterolemia Clinical Trial
Official title:
Effect of Red Yeast Rice, Phytosterols and L-tyrosol on Lipid Profile and Endothelial Function: a Double-blind, Placebo-controlled, Randomized Clinical Trial
A large body of evidence confirm the cholesterol lowering effect of red yeast rice, phytosterols and L-tyrosol. Because their mechanisms of action mime the ones of chemical statins and cholesterol absorption inhibitors, it is plausible that their association will provide a more relevant (and safe) LDL cholesterolemia reduction.
European Food Safety Authority approves some health claim related to the cardiometabolic
effects of some nutraceuticals, and in particular of red yeast rice, phytosterols and
L-tyrosol.
In a previous study the investigators have already demonstrated the synergistic effect of
red yeast rice and phytosterols in term of lipid-lowering activity.
Preliminary data suggest that these nutraceuticals could also exert a positive effect on
vascular health beyond the direct effects on serum lipids.
No data are available on the combined effects of these dietary supplement in humans.
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