Improved Patient Recovery After Anesthesia With Hypercapnia Hyperpnoea

Status Completed

Clinical Trial Summary

The proposed study will measure the time from the end of surgery until the time patients meet the discharge criteria from the postoperative anesthesia care unit and the time from the end of surgery until the patients regained cognitive function after anesthesia.

Clinical Trial Description

Hypercapnia has been used in conjunction with hyperpnoea to provide a more rapid return of responsiveness after inhaled anesthesia. In our first clinical study with isoflurane we confirmed that the time from turning off the vaporizer to opening of eyes was shortened by an average of 62% when the minute ventilation was elevated and the end tidal carbon dioxide concentration was kept at 52 mmHg rather than 28 mmHg during emergence. In our second study we found that hypercapnia and hyperpnoea accelerated recovery proportionately for sevoflurane and desflurane. The benefits of accelerating subject recovery in the operating room may extend to the entire recovery period if the subject is more alert and easier to care for when they arrive in the post anesthesia care unit. ;

Study Design

Related Conditions & MeSH terms

Hypercapnia

Clinical Trial Details

NCT number	NCT00708526
Study type	Interventional
Source	University of Utah
Contact
Status	Completed
Phase	N/A
Start date	March 2008
Completion date	November 2008

View Details

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