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Hyperbilirubinemia clinical trials

View clinical trials related to Hyperbilirubinemia.

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NCT ID: NCT06227624 Completed - Neonatal Jaundice Clinical Trials

Role of Oral Zinc in Reducing Neonatal Indirect Hyperbilirubinemia

Start date: June 1, 2018
Phase: Phase 3
Study type: Interventional

This study aimed to determine the role of oral zinc in reducing the neonatal indirect hyperbilirubinemia if used concomitant with the standard phototherapy

NCT ID: NCT06173856 Completed - Clinical trials for Hyperbilirubinemia, Neonatal

Effectiveness of Phototherapy With and Without Probiotics

Start date: January 10, 2022
Phase: N/A
Study type: Interventional

Raised serum bilirubin levels can cause kernicterus and premature infants are at increased risk due to metabolic immaturity. The standard treatment for neonatal jaundice is phototherapy but probiotics along with it can reduce the duration of phototherapy and hospitalization stay, secondarily can reduce the risk of nosocomial infection.

NCT ID: NCT06105879 Completed - Clinical trials for Hyperbilirubinemia, Neonatal

Transcutaneous Bilirubin Levels From Covered Skin

Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

The aim of this study was to evaluate the levels of total serum bilirubin and transcutaneous bilirubin in newborns, measured in both covered and exposed areas, before phototherapy, 24th hour of phototherapy and 8 hours after cessation of phototherapy. The study included term and preterm newborns that required phototherapy between postnatal days 0-28. Total serum bilirubin levels and transcutaneous bilirubin measurements were obtained using the MBJ20-2019 Transcutaneous Handheld Bilirubinometer (Beijing M&B Electronic Instruments Co. Ltd. China, 2019) from both exposed (sternal) and unexposed (forehead, covered with a radio-opaque patch) areas before, at 24th hours and eight hours after phototherapy.

NCT ID: NCT06018012 Completed - Clinical trials for Neonatal Hyperbilirubinemia

MRA and ABR as Early Predictors of Bilirubin-Induced Neurologic Dysfunction in Full-term Jaundiced Neonates

Start date: March 1, 2019
Phase:
Study type: Observational

The aim of the research was to define the role of MRS and ABR as early predictors of bilirubin-induced neurologic dysfunction (BIND) in full-term neonates who required intervention (phototherapy or exchange transfusion).

NCT ID: NCT05692648 Completed - Newborn Jaundice Clinical Trials

Effect of Repositioning Frequency Neonates Receiving Phototherapy

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

Purpose: The present study was conducted to determine the effect of repositioning frequency during phototherapy on bilirubin level and neonates comfort. Design and methods: This was a single-centered, single-blind, 3-arm, pretest-posttest parallel-group randomized controlled trial conducted in a neonatal intensive care unit. Participants were randomly assigned to one of three groups: Supine position group (n = 20), hourly position change group (n = 20), and control group (n = 20). The bilirubin level and comfort levels of the neonates were evaluated.

NCT ID: NCT05356273 Completed - Clinical trials for Hyperbilirubinemia, Neonatal

The Effect of Massage on the Bilirubin Level in Term Infants Receiving Phototherapy

Start date: October 1, 2021
Phase: N/A
Study type: Interventional

Background: It has been reported in the current literature that massage has various positive physiological effects on the newborn. Also baby massage; It increases the collection and excretion of waste products such as bilirubin by accelerating the flow of blood, lymph and tissue fluids. Our aim is to investigate the effect of infant massage on hyperbilirubinemia in newborns receiving phototherapy. Method: The population of the study consisted of babies who were hospitalized in Istanbul Haseki Training and Research Hospital Neonatal Intensive Care Unit between October 2021 and January 2022 and needed phototherapy. Transcutaneous bilirubin device and data collection form were used to obtain the data. 61 newborns who met the study criteria were randomly divided into experimental (n=30) and control (n=31) groups. Phototherapy was applied to all babies twice a day. In addition to phototherapy, infant massage was applied to the experimental group for 10 minutes just before the phototherapy. Bilirubin level measurements were made 2 hours after the end of phototherapy for both groups. Diaper changes for both groups were carried out 8 times a day, every 3 hours.

NCT ID: NCT05260138 Completed - Clinical trials for Hyperbilirubinemia, Neonatal

Bundling Gentle Body Massage Along With Regular Position Change Under Phototherapy

Start date: August 20, 2021
Phase: N/A
Study type: Interventional

This study aimed to investigate the effect of bundling gentle body massage along with regular position change on bilirubin level and clinical outcomes among full-term neonates with hyperbilirubinemia under phototherapy. Hypothesis Full-term neonates with hyperbilirubinemia who receive gentle body massage along with regular position change exhibit less bilirubin level and better clinical outcomes than those who don't.

NCT ID: NCT05121311 Completed - Newborn Jaundice Clinical Trials

Assessment of Neonatal Hyperbilirubinemia by NeoprediX B.1 Algorithm

Bili-PrediX1
Start date: August 9, 2021
Phase:
Study type: Observational

Due to actual standard of neonatal care bilirubin is monitored in neonates several times after birth to avoid hyperbilirubinemia. As the peak is often one or two days after discharge from hospital a more precise predication than the actual one is desirable to avoid needlessly follow-ups. The precision of an algorithm to predict bilirubin values 24-48h into the future is evaluated in this study.

NCT ID: NCT05077787 Completed - Clinical trials for Neonatal Hyperbilirubinemia

Tactile and Kinaesthetic Stimulation in Neonates With Hyperbilirubinaemia

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

Hyperbilirubinemia is the most common problem seen in neonates, owing to severe complications in their lifetime. The study design of the study is pretest - a posttest experimental design. Criterion-based purposive sampling will be used for recruiting the neonates. In the study neonates will be selected according to the selection criteria and will be allocated into two groups using computer-based randomization.The Intervention group - neonates will receive tactile and kinesthetic stimulation for 15 minutes for 3 consecutive days, 1 hour after feeding twice daily along with Phototherapy, Control group - Phototherapy alone will be given along with conventional NICU care. Total serum bilirubin will be assessed as outcome measures daily once. Transcutaneous bilirubin will be assessed after every intervention.

NCT ID: NCT04792996 Completed - Clinical trials for Mild Hyperbilirubinaemia

Preventive Potential of Bilirubin

BILIHEALTH
Start date: June 1, 2014
Phase:
Study type: Observational

The prevalence of mild hyperbilirubinemia, also known as Gilbert´s Syndrome, is usually defined using an unconjugated bilirubin (UCB) blood concentration above 17.1 µmol/l. The prevalence of GS is remarkably common, affecting 5-10% (depending on ethnicity and gender) of the adult population. The aim of this project is to investigate whether there is a difference in health related marker between 60 subjects with Gilbert´s Syndrome (mild hyperbilirubinaemia) and 60 age and gender matched control subjects.