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Hyperbilirubinemia, Neonatal clinical trials

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NCT ID: NCT05365984 Not yet recruiting - Clinical trials for Hyperbilirubinemia, Neonatal

Intelligent Follow-up of Neonatal Jaundice Based on Early Indicators and Internet Communications

Start date: May 2022
Phase: N/A
Study type: Interventional

In this prospective multi-center randomized clinical trial, a new follow-up strategy for neonatal jaundice after discharge will be evaluated. It is based on current risk factors of neonatal hyperbilirubinemia, added with the rate of bilirubin production (exhaled carbon monoxide measurement) as a new indicator,and incorporated with Internet Plus technology. Traditional methods following the Chinese guideline for neonatal hyperbilirubinemia were applied in the control group. The morbidity of BIND, the number of outpatient follow-up after discharge and the convenience will be compared between the two groups. The accuracy, effectiveness, safety and convenience of the study strategy will be testified.

NCT ID: NCT04868019 Not yet recruiting - Clinical trials for Hyperbilirubinemia, Neonatal

Role of Fenofibrate in Indirect Neonatal Hyperbilirubinemia: a Randomized Control Trial

Start date: September 2021
Phase: N/A
Study type: Interventional

Fenofibrate accelerates bilirubin conjugation and excretion, decreasing the side effects of prolonged unconjugated hyperbilirubinemia in neonates. It also reduces the duration of phototherapy and thus the duration of stay in the hospital. This research is carried out to improve standard protocol for the management of neonatal hyperbilirubinemia in the local settings.

NCT ID: NCT04585828 Not yet recruiting - Clinical trials for Neonatal Hyperbilirubinemia

Comparison of Double Pad Fiber Optic Device Versus Conventional Phototherapy

Start date: October 2020
Phase: N/A
Study type: Interventional

A randomized study of phototherapy for neonatal hyperbilirubinemia. The intervention group is treated with a double pad fiber optic device and the control group with conventional blue ligt phototherapy from above. Both treatments are well known and used. The primary outcome is to explore the parents experience with the two different treatment modalities by questionnaires.

NCT ID: NCT04445675 Not yet recruiting - Jaundice, Neonatal Clinical Trials

The Effect of Breastfeeding Support on Hospitalization Due to Jaundice

Breastfeeding
Start date: August 1, 2020
Phase: N/A
Study type: Interventional

Neonatal jaundice is the most common reason for rehospitalization after postnatal discharge. Jaundice due to breastfeeding failure is an important subtype of pathological neonatal jaundice. Typically, it occurs with lactation failure, which results in dehydration (reducing urine output), significant weight loss (>10% of birth weight) and sometimes hypernatremia, during the first postnatal week. Jaundice caused by breastfeeding failure is observed in one third (31.8%) of total cases of pathological neonatal jaundice requiring rehospitalization. Jaundice lasts for an average of 6.8 days and the length of hospital stay takes up to 3 days. Jaundice due to breastfeeding failure requires focused efforts for a program structured with breastfeeding education and special breastfeeding support. This support causes the role of nurses to become even more important. The aim of this study is to investigate the effect of support provided for breastfeeding and the feeding of infants' with breast milk on hospitalization due to jaundice. Research Hypotheses: H0: The support provided for breastfeeding and the feeding of infants' with breast milk has no effect on hospitalization due to jaundice. H1: The support provided for breastfeeding and the feeding of infants' with breast milk affects the consequences of hospitalization due to jaundice.

NCT ID: NCT04246229 Not yet recruiting - Clinical trials for Neonatal Hyperbilirubinemia

Transcutaneous Bilirubinometry and Phototherapy

TRABIN
Start date: January 1, 2024
Phase: N/A
Study type: Interventional

A randomized Controlled trial comparing the use of transcutaneous bilirubinometry to serum bilirubin measurements (via blooddraws = standard care) in neonates born after a gestational age > 32 weeks and < 15 days of age treated with Phototherapy for neonatal hyperbilrubinemia. Main outcome measurement is the number of blooddraws for measurement of bilirubin. Secondary outcome measurements are duration of phototherapy and hospitalisation.