Hydrocephalus Clinical Trial
Official title:
Comparison of Benefit and Survival for Different Etiologies of Adult Patients With Hydrocephalus Between Programmable Cerebrospinal Fluid Ventricular Shunt and Non-programmable Cerebrospinal Fluid Ventricular Shunt
Programmable valve (PV) has been shown as a solution to the high revision rate in pediatric hydrocephalus patients, but it remains controversial among adults. This study is to compare the overall revision rate, revision cause, and revision-free survival between PV and non-programmable valve (NPV) in adult patients with different hydrocephalus etiologies.
Relatively high revision rates up to 32% of CSF shunting operations remained an unsolved problem for neurosurgeons. The cause of revisions were diverse, including overdrainage/underdrainage, shunting system obstruction, infection or technical skill related. Programmable valve (PV) has been shown as a solution to the high revision rate in pediatric hydrocephalus patients, but it remains controversial among adults. This study is to compare the overall revision rate, revision cause, and revision-free survival between PV and non-programmable valve (NPV) in adult patients with different hydrocephalus etiologies. The investigators reviewed the chart of all patients with hydrocephalus receiving index ventricular CSF shunt operations conducted at a single institution in northern Taiwan from January 2017 to December 2017. Patients included in the study were followed up for at least five years. Statistical tests including independent t-test, Chi-square test and Fisher's exact test were used for comparative analysis, and Kaplan-Meier curve using log-rank test was performed to compare the revision-free survival between the PV and NPV groups ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT06040697 -
Formative Usability Assessment of Wireless Thermal Anisotropy Devices
|
||
| Terminated |
NCT02408757 -
Sonographic Monitoring of Weaning of Cerebrospinal Fluid Drainages
|
||
| Terminated |
NCT01863381 -
Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement
|
N/A | |
| Completed |
NCT00652470 -
A Study Comparing Two Treatments for Infants With Hydrocephalus
|
Phase 2 | |
| Completed |
NCT00196196 -
A Precision and Accuracy Study of the Codman Valve Position Verification (VPV) System.
|
Phase 3 | |
| Terminated |
NCT05501002 -
Pilot Study to Evaluate the CereVasc® eShunt® System in the Treatment of Communicating Hydrocephalus
|
N/A | |
| Active, not recruiting |
NCT05068128 -
Combined Flow and Pressure Study of Craniospinal Dynamic
|
||
| Completed |
NCT04496414 -
Bactiseal Catheter Safety Registry in China
|
||
| Terminated |
NCT02900222 -
Study of Choroid Plexus Cauterization in Patients With Hydrocephalus
|
N/A | |
| Recruiting |
NCT04099823 -
MR Evaluation of Cerebrospinal Fluid (CSF) Dynamics
|
N/A | |
| Unknown status |
NCT02775136 -
An Evaluation of a Non-invasive Brain Monitor
|
N/A | |
| Completed |
NCT00692744 -
Quality of Life in Elderly After Aneurysmal Subarachnoid Hemorrhage (SAH)
|
N/A | |
| Recruiting |
NCT04758611 -
The ETCHES I Study (Endovascular Treatment of Communicating Hydrocephalus With an Endovascular Shunt)
|
N/A | |
| Completed |
NCT03595033 -
Hydrocephalus iPad-App Based Intervention Study
|
N/A | |
| Completed |
NCT04207229 -
CERTAS Programmable Valve Registry
|
||
| Terminated |
NCT01973764 -
Intraventricular Drain Insertion: Comparison of Ultrasound-guided and Landmark-based Puncture of the Ventricular System
|
N/A | |
| Completed |
NCT01976559 -
Comparison of Continuous Noninvasive and Invasive Intracranial Pressure Measurement--Celda Infusion Subprotocol
|
N/A | |
| Completed |
NCT02381977 -
Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment
|
N/A | |
| Recruiting |
NCT06086561 -
Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device
|
N/A | |
| Recruiting |
NCT05910944 -
European Study of Prodromal iNPH
|