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Hydrocephalus, Normal Pressure clinical trials

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NCT ID: NCT01092546 Terminated - Clinical trials for Normal Pressure Hydrocephalus

Positron Emission Tomography Imaging of Brain Amyloid in Normal Pressure Hydrocephalus

Start date: March 2010
Phase: Phase 3
Study type: Interventional

To determine the level of association between the quantitative estimates of brain uptake of [18F]flutemetamol and the quantitative immunohistochemical and histochemistry estimates of amyloid levels in frontal lobe biopsy samples obtained from subjects during shunt placement for NPH.

NCT ID: NCT01053312 Completed - Clinical trials for Normal Pressure Hydrocephalus

PET Imaging of Brain Amyloid in Normal Pressure Hydrocephalus

Start date: December 2009
Phase: Phase 3
Study type: Interventional

This study will determine the level of association between the quantitative estimates of brain uptake of [18F]flutemetamol and the quantitative immunohistochemical estimates of amyloid levels in biopsy samples previously obtained during shunt placement in patients who have normal pressure hydrocephalus (NPH).

NCT ID: NCT00946127 Terminated - Hydrocephalus Clinical Trials

ETV Versus Shunt Surgery in Normal Pressure Hydrocephalus

Start date: March 2009
Phase: Phase 3
Study type: Observational

The purpose of this study is to test and compare the efficacy of Endoscopic Third Ventriculostomy with shunting of Cerebrospinal fluid (CSF)for treatment for patients of Normal pressure Hydrocephalus.

NCT ID: NCT00874198 Unknown status - Clinical trials for Normal Pressure Hydrocephalus

European Study on Prediction of Outcome in Patients With Idiopathic Normal Pressure Hydrocephalus

Start date: October 2004
Phase: N/A
Study type: Interventional

The purpose of the study is to determine the predictive values and prognostic accuracies of CSF dynamic measures, the TAP -TEST (high-volume cerebrospinal fluid withdrawal), resistance to CSF outflow and compliance in the prediction of shunt-treatment outcome in patients with idiopathic normal pressure hydrocephalus.

NCT ID: NCT00793416 Withdrawn - Clinical trials for Normal Pressure Hydrocephalus

ShuntCheck Accuracy in Detecting Shunt Obstruction Normal Pressure Hydrocephalus (NPH) Patients

Start date: November 2008
Phase: Phase 4
Study type: Interventional

The purpose of this study is to examine the role of ShuntCheck and MR Imaging in evaluating the presence or absence of Shunt Obstruction in the patients of Hydrocephalus or Idiopathic Intracranial Hypertension (IIH) undergoing radionuclide test for suspected shunt obstruction. This is an exploratory study to determine how a non-invasive device can assist in detection of presence of flow in these patients.

NCT ID: NCT00727142 Terminated - Clinical trials for Normal Pressure Hydrocephalus

Conservative Versus Surgical Management of Idiopathic Normal Pressure Hydrocephalus (INPH)

Start date: July 2008
Phase: N/A
Study type: Interventional

This study aims to provide class 1 evidence supporting or refuting the existence of normal pressure hydrocephalus.

NCT ID: NCT00613886 Terminated - Clinical trials for Normal Pressure Hydrocephalus

Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus

NPH
Start date: March 2006
Phase: N/A
Study type: Interventional

The research project is designed to determine which combination of tests will enable physicians to predict whether a patient with symptoms of normal pressure hydrocephalus (NPH) will improve with a shunt.

NCT ID: NCT00600795 Completed - Clinical trials for Normal Pressure Hydrocephalus

Prognostic Value of Transforming Growth Factor-Beta 1 in Normal Pressure Hydrocephalus

Start date: January 2008
Phase: N/A
Study type: Observational

Correlation of cerebrospinal fluid levels of transforming growth factor beta-1 with functional improvements after insertion of ventriculoperitoneal shunt for normal pressure hydrocephalus

NCT ID: NCT00494689 Recruiting - Cognitive Function Clinical Trials

Transcranial and Rapid Magnetic Stimulation for Gait Apraxia Due to Normal Pressure Hydrocephalus and Cerebral Ischemia

Start date: January 2002
Phase: N/A
Study type: Observational

The investigator(neurologist) has published a study in International Congress Series, in the 15th International Conference of Biomagnetism Vancouver Proceedings 2006,and Science Direct website, of 15 patients with brain ischemia and dilated ventricles who improve when treated with transcranial monitoring or low ultrasound wave intensity (milliwatts) and with rapid magnetic stimulation which is also a diagnostic tool routinely used by many neurophysiologists. Before, these patients will progress and may need a brain shunt called Ventriculo-peritoneal shunt. He and collaborators now would like to do a double study as this appears to be a cheap and effective alternative treatment and help patients to walk again.

NCT ID: NCT00233701 Completed - Clinical trials for Normal Pressure Hydrocephalus

Normal Pressure Hydrocephalus (NPH) Registry

Start date: October 2004
Phase: Phase 4
Study type: Observational

The overall aim of the registry is to develop a longitudinal, observational database that is focused on adult patients with Normal Pressure Hydrocephalus (NPH) that can be used as a source of clinical information for individual surgeons, as well as a national data repository for scientific inquiry and publications.