Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to determine the impact of Nuun electrolyte tablets on hydration status in young and active men and women. We will follow a similar approach as used by Maughan and colleagues (2016) to measure the beverage hydration index (the relative amount of urine passed after consumption of a drink compared to water). It is hypothesized that Nuun electrolyte tablets will result in a greater hydration status as compared to water only. Due to the fact that athletes use Nuun tablets at varying dosages, we will evaluate Nuun at both a single dosage and a double dosage. We maintain a non-directional hypothesis regarding the potential differences between the two different dosages tested.


Clinical Trial Description

Maintaining adequate hydration is essential to optimal health and athletic performance. When individuals exercise (in particular in a warm environment), they can lose excessive amounts of fluids through sweating, along with necessary electrolytes (e.g., sodium, potassium, chloride). With dehydration, individuals may feel sluggish and can experience impaired physical performance. Many attempts have been made to improve and measure the hydration status of active individuals. This typically involves the ingestion of fluids leading up to activity (typically plain water), as well as the ingestion of fluids during the activity itself (water, along with a diluted carbohydrate/electrolyte beverage). This approach seems to work well; however, some debate remains over what the best fluid is to consume, in particular related to the macronutrient type and the specific electrolyte mix. Related to the above, it is well-accepted that electrolyte replenishment is of importance, both during and following exercise-to aid in rehydration for subsequent bouts. The use of electrolytes (sodium in particular) has been used for decades to aid athlete hydration and has led to the development of various sport drinks-which also include small amounts of carbohydrate. However, one problem with carbohydrate ingestion is that some individuals experience gastrointestinal (GI) upset following carbohydrate ingestion before and during an event, despite very good physical performance outcomes. Due to this GI upset, some individuals (in particular recreationally active individuals who are not competing at high levels) rely solely on water and seek a method to ingest the lost electrolytes. In addition, some individuals prefer to have both plain water and an electrolyte beverage during their training/competition sessions and in some activities (e.g., running, cycling), carrying multiple bottles of fluid is difficult. The solution to the above issues for many athletes is the use of electrolyte tablets. These can be dropped into plain water and will dissolve into a flavored electrolyte-rich beverage. They are easy to transport and provide the needed electrolytes to replace those that are lost through intense and/or long duration exercise. Nuun electrolyte tablets provide only 2 grams of carbohydrate and a combination of electrolytes, provided at a relatively low percentage of the Daily Value (DV). The DV tells us how much a particular nutrient in a serving of a food product contributes to a daily diet, based on a standard 2000 calorie diet. Nuun tablets contain: calcium (13mg, 1%DV), sodium (300mg, 13%DV), potassium (150mg, 3%DV), magnesium (25mg, 6%DV), and chloride (40mg, 2%DV). These tablets contain a small percentage of the needed total electrolytes but adequate amounts to replace lost electrolytes as a result of physical activity. While Nuun tablets are commercially available and have received positive reviews from end users, there have been no studies to date to evaluate the impact of these tablets on hydration status. Therefore, the purpose of this study is to determine the impact of Nuun electrolyte tablets on hydration status in young and active men and women. We will follow a similar approach as used by Maughan and colleagues to measure the beverage hydration index (the relative amount of urine passed after consumption of a drink compared to water). It is hypothesized that Nuun electrolyte tablets will result in a greater hydration status as compared to water only. Due to the fact that athletes use Nuun tablets at varying dosages, we will evaluate Nuun at both a single dosage and a double dosage. We maintain a non-directional hypothesis regarding the potential differences between the two different dosages tested. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04422158
Study type Interventional
Source University of Memphis
Contact
Status Completed
Phase N/A
Start date June 3, 2020
Completion date August 18, 2020

See also
  Status Clinical Trial Phase
Completed NCT05111392 - Hydration Dynamics and Influence of Beverage Composition Phase 1/Phase 2
Completed NCT02671149 - The Effect of Small Changes in Hydration on Cognition N/A
Completed NCT05272540 - Changes in Body Water During Surgery
Completed NCT05352724 - Clinical Trial to Evaluate the Efficacy of a Sport Drink After High-intensity Aerobic Exercise N/A
Recruiting NCT05569044 - Oral Rehydration Solutions in Healthy Adult Athletes N/A
Active, not recruiting NCT06170554 - Study of Hydration Levels in Sports and Non-sports Schoolchildren (EHC)
Completed NCT01360333 - Oral Fluid Volume Expansion N/A
Completed NCT03769779 - Evaluation of the Benefits of FloraGLO™ Lutein on Skin Health N/A
Completed NCT04460846 - Evaluation of Hydration Status When Consuming Alkaline Water Compared to Reverse Osmosis Purified Water. N/A
Not yet recruiting NCT06062017 - Potassium, Hydration, Cardiovascular, and Kidney Study N/A
Completed NCT02160873 - Nighttime Feeding and Morning Endurance Performance N/A
Recruiting NCT05939193 - Effect of Urine-guided Hydration on Acute Kidney Injury After CRS-HIPEC N/A
Completed NCT04012372 - ROSA Oligomineral Water for Oral Hydration in 6-Month-Old Healthy Infants N/A
Completed NCT05451446 - The Effect of Proprietary Water on Physiological and Perceptual Responses N/A
Recruiting NCT06361771 - Evaluation of Invisible Preparation Behaviors of Middle and High School Students in Sports Facilities (PRICELESS)
Recruiting NCT06185595 - Effect of Glycerol-Electrolyte Beverages on Fluid Balance in Healthy Euhydrated Men and Women at Rest N/A
Completed NCT05510791 - Impact of Nuun SPORT on Subjective Exercise Performance in Male and Female Runners N/A
Completed NCT03525470 - Autonomic Adaptations to Hydration and Brain Functioning N/A
Completed NCT04764565 - Impact of Nuun Instant on Hydration Status in Active Men and Women N/A
Withdrawn NCT03526367 - A Randomized Trial of Rosuvastatin Loading Combined With Early hydrAtion Versus Standard-of-care Medications for the Prevention of CIAKI in Patient With AMI Undergoing Emergency PCI Phase 4