The Effect of Video Game Exercise on Dynamic Balance and Gait in Individuals With Huntington's Disease

Huntington's Disease Clinical Trial

Official title:

The Effect of Video Game Biofeedback Modulated Exercise (ViBE)on Dynamic Balance and Gait in Individuals With Huntington's Disease

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01735981
• Other study ID #: 2008H0109
• Status: Completed
• Phase: N/A
• Start date: June 2008
• Est. completion date: June 2012

Study information

• Verified date: July 2021
• Source: Ohio State University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To examine the benefits of using a video-game, Dance, Dance, Revolution, as an exercise modality to improve gait and balance in individuals with Huntington's disease.

Description:

The primary purpose of this study was to determine the effectiveness of a therapist-guided Video-game Biofeedback Modulated Exercise (ViBE) program administered via Dance Dance Revolution to improve dynamic balance, gait and mobility in individuals with Huntington's Disease. Secondary aims were to explore whether the ViBE intervention would improve quality of life, fall risk, and neuropsychological functions. The investigators hypothesized that the video-game program would lead to greater improvements in walking, dynamic balance, quality of life, fall risk, and neuropsychological function than a control handheld video game program. Since motivation is essential to the long-term maintenance of an exercise program the investigators were also interested in finding out how successful people with Huntington's Disease were at playing Dance Dance Revolution, what their perceptions were of playing the game, and whether they thought that it was beneficial

Recruitment information / eligibility

• Status: Completed
• Enrollment: 24
• Est. completion date: June 2012
• Est. primary completion date: November 2010
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 79 Years

Eligibility

Inclusion Criteria:

• adults 18 - 79 with a diagnosis of Huntington's disease

Exclusion Criteria:

• cannot walk 10 feet without assistance, any other neurologic condition

Related Conditions & MeSH terms

• Huntington Disease
• Huntington's Disease

Intervention

Other:
• Video game exercise using Dance Dance Revolution
use of the video-game, Dance, Dance Revolution as an exercise to improve gait and balance
• hand-held video game
hand-held video games

Locations

Country	Name	City	State
United States	The Ohio State University Atwell Hall	Columbus	Ohio

Sponsors (1)

Lead Sponsor	Collaborator
Anne Kloos

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: forward velocity.	6 weeks
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: forward stride length.	6 weeks
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: forward swing percent.	6 weeks
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: forward double support percent.	6 weeks
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: forward heel to heel base of support.	6 weeks
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: backwards velocity.	6 weeks
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: backwards stride length.	6 weeks
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: backwards swing percent.	6 weeks
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: backwards double support percent.	6 weeks
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: backwards heel to heel base of support.	6 weeks
Primary	Gait Parameters	utilized GAITRite to obtain spatiotemporal measures of gait: obstacle velocity.	6 weeks
Secondary	Tinetti Mobility Test	Observation of gait and balance with quantifiable 16-item assessment with an ordinal scale of 0-2 for up to a total score of 32, with higher scores indicating better performance. It is reliable and predicts falls among those with Parkinson's disease and Huntington's disease.	6 weeks
Secondary	Four Square Step Test	Examines ability to step over an object in multiple directions and is timed. Participants are instructed to step over a cane into each square in a specific order. Faster times indicate better balance. It has been shown to predict falls in the elderly.	6 weeks
Secondary	Activities-Specific Balance Confidence Scale	Individuals rate their balance confidence from 1-100 on 16 tasks and total score is the mean; higher scores indicate greater confidence and lower fall risk. The Activities-Specific Balance Confidence Scale is reliable and valid in elderly and neurological populations.	6 weeks
Secondary	World Health Organization Quality of Life	This questionnaire is a measure of quality of life addressing 4 domains including physical, psychological, social, and environment health. Responses on 26 items are on a five-point scale (from 1 = very dissatisfied to 5 = very satisfied) and each item is added to achieve a total score for each domain. The mean score for each domain is calculated then multiplied by 4 to get the domain score which are then transformed to a scaled score of 0-100 comparable to the original WHOQOL-100 therefore a total score between 0-400 with high scores indicating better quality of life. The WHOQOLBref has good reliability and validity.	post intervention and post hand-held game, each lasts 6 weeks