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Clinical Trial Summary

Primary objective:

- The primary objective of the study is to establish that riluzole slows down (1) the decrease in total functional capacity (TFC), (2) the increase of the motor score of the Unified Huntington's Disease Rating Scale (UHDRS) as well as (3) the increase of a combined score of these.

Secondary objectives:

Secondary objectives are to assess

- changes in the other UHDRS subscales

- the number of patients who need antichoreic treatment and the time until this treatment has to be initiated

- the safety/tolerability of riluzole in Huntington patients


Clinical Trial Description

n/a


Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT00277602
Study type Interventional
Source Sanofi
Contact
Status Completed
Phase Phase 3
Start date November 1999
Completion date July 2004

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