Hunger Clinical Trial
Official title:
Einfluss Des süßmodulierenden Polyphenols Hesperetin in Kombination Mit Saccharose Auf Die Blutglukose-Regulierung Und Energieaufnahme in Abhängigkeit Der Süßwahrnehmung Teil 2
The aim of this cross-over intervention study is to investigate the influence of hesperetin applied in combination with sucrose in comparison to an equally sweet-tasting sucrose-only solution and an isocaloric sucrose-only solution on markers of energy metabolism
Status | Recruiting |
Enrollment | 45 |
Est. completion date | March 31, 2025 |
Est. primary completion date | August 31, 2024 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 45 Years |
Eligibility | Inclusion Criteria: - healthy - non-smoking - normal taste responses towards sweet taste Exclusion Criteria: - pregnancy or breast-feeding - regular smokers - disturbed glucose and/or lipid metabolism - regular intake of medication - known allergies against one of the test compounds - ageusia alcohol or drug addiction intake of antibiotics within the past 2 months |
Country | Name | City | State |
---|---|---|---|
Austria | Christian Doppler Laboratory for Taste Research | Vienna |
Lead Sponsor | Collaborator |
---|---|
University of Vienna |
Austria,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in blood glucose concentration | Change compared to baseline in blood glucose concentration [mg/dL] in plasma samples after drinking the test solution | 15, 30, 60, 90, and 120 minutes after drinking the test solution | |
Primary | Change in appetite score | Change compared to baseline in the subjective rating of the individual feeling of hunger, fullness, as well as appetite for a snack or for something sweet on a unstructured, digital visual analog scale ranging from 0-10 cm in comparison to baseline | Difference between before and 120 minutes after drinking of the test solution | |
Primary | Change in food intake | Ad libitum food intake from a standardized breakfast | 120 minutes after drinking of the test solution | |
Secondary | Change in regulating hormones | Change compared to baseline in Insulin, Glucagon-like peptide 1, Gastric inhibitory polypeptide, and Polypetide Y concentrations [mmol/L] in plasma samples after drinking the test solution | 15, 30, 60, 90, and 120 minutes after drinking the test solution |
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT06061419 -
The Effect of Huel Powder on Appetite
|
N/A | |
Completed |
NCT03850990 -
Effect of Gut-Cued Eating on BMI and Efficacy of Open-Label Placebo to Augment Weight Loss
|
N/A | |
Completed |
NCT02827318 -
Eating Disinhibition and Vagal Tone and the Postprandial Response to Glycaemic Load
|
N/A | |
Recruiting |
NCT03978975 -
Water Exercise and Health (WATHEALTH)
|
N/A | |
Active, not recruiting |
NCT06082778 -
ZOE's Ferment Experiment
|
N/A | |
Completed |
NCT05734209 -
How Does Eating Behavior and Hunger in Virtual Reality Meals Compare to Real Meals?
|
N/A | |
Completed |
NCT02948816 -
The Effects of Social Media on Food Intake and Behaviour
|
N/A | |
Completed |
NCT03900130 -
The Omnibus Satiety Metric: Predicting Satiety in Humans Through Brain, Blood, and Subjective Data
|
N/A | |
Recruiting |
NCT05196763 -
Maximizing Nutrition Education to Meet Dietary and Food Security of Children and Parents
|
N/A | |
Completed |
NCT03489226 -
Capsimax Effect on Metabolic Rate, Satiety and Food Intake
|
N/A | |
Completed |
NCT03656146 -
Food for Thought: Food Insecurity Screening in the Emergency Department
|
N/A | |
Completed |
NCT01809925 -
Study of Psyllium 6.8 g Versus Placebo on Satiety in Healthy Volunteers
|
N/A | |
Completed |
NCT01562678 -
Liraglutide in Obesity and Diabetes: Identification of CNS Targets Using fMRI
|
Phase 4 | |
Completed |
NCT04884373 -
Patient Satiety as an Indicator of Stomach Contents and Fluid Volume
|
||
Completed |
NCT02505490 -
The Effect of Television Watching on Liking of Food
|
N/A | |
Completed |
NCT02577705 -
Building Wealth and Health Network: A Microfinance/TANF Demonstration Project
|
N/A | |
Recruiting |
NCT03537781 -
The Effect of Food Labelling and Satiety on Individuals Food Choice
|
N/A | |
Completed |
NCT02477410 -
Effects of Hydrolysed Porcine Proteins on Muscle Protein Synthesis and Appetite
|
N/A | |
Completed |
NCT01924130 -
School Breakfast Policy Initiative Study
|
N/A | |
Completed |
NCT01413217 -
Which is a Better Breakfast? Egg or Cereal?
|