Human Volunteers Clinical Trial
Official title:
In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome.
Muscular compartment syndrome (MCS) is consecutive to an increase in intramuscular
compartment pressures, and is a rare but serious postoperative complication.
The INVOS (In Vivo Optical Spectroscopy) monitors tissular oxygenation continuously and
non-invasively.
The objective is to develop a model mimicking the physiopathology of MCS to assess the
interest of the INVOS in this case.
After inflation of a tourniquet (pressure equal to the mean arterial pressure, we will obtain a model of slight venous congestion and arterial hypoperfusion. A comparison will be made between INVOS monitoring, sensory deficits, pain, electromyography and invasive pressure. ;
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Basic Science
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